NASDAQ: APRE
Aprea Therapeutics Inc Stock

$0.78+0.01 (+1.3%)
Updated Sep 14, 2026
APRE Price
$0.78
Fair Value Price
$2.23
Market Cap
$9.83M
52 Week Low
$0.55
52 Week High
$1.69
P/E
-0.75x
P/B
0.26x
P/S
8,023x
PEG
N/A
Dividend Yield
N/A
Revenue
$5.19k
Earnings
-$12.31M
Gross Margin
100%
Operating Margin
-245,156.76%
Profit Margin
-237,362.8%
Debt to Equity
0.1
Operating Cash Flow
-$12M
Beta
0.6
Next Earnings
N/A
Ex-Dividend
N/A
Next Dividend
N/A

APRE Overview

Aprea Therapeutics, Inc. is a biopharmaceutical company in its clinical development stage, dedicated to discovering and marketing innovative cancer treatments. Their therapeutic approach centers on modulating DNA damage response pathways. The company's primary drug candidate, ATRN-119, is an oral ATR inhibitor currently undergoing Phase 1/2a clinical trials for patients with advanced solid tumors. Beyond this lead compound, Aprea's developmental pipeline includes ATRN-Backup, which is also an ATR inhibitor; ATRN-W1051, being explored for its anti-tumor effects; and ATRN-DDRi. Aprea Therapeutics, Inc. is headquartered in Boston, Massachusetts.

Zen Rating

Our proven quant model uses 115 proprietary factors, including AI, to determine APRE's potential to beat the market

Zen Rating Component Grades

N/A
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Industry: Biotech

Industry Rating
F
APRE
Ranked
Unranked of 459

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APRE News

Overview

Due Diligence Score

Industry Average (24)
You've viewed Due Diligence Score for 10/10 free stocks. Upgrade to Premium to see how APRE scored across 33 valuation, financial, forecast, performance, and dividend due diligence checks.

Due Diligence Checks

APRE ($0.78) is undervalued by 65.02% relative to our estimate of its Fair Value price of $2.23 based on Discounted Cash Flow (DCF) modelling, but does not have a significant margin of safety
Below Fair Value Valuation
APRE ($0.78) is significantly undervalued by 65.02% relative to our estimate of its Fair Value price of $2.23 based on Discounted Cash Flow (DCF) modelling, which includes a healthy margin of safety
Significantly Below Fair Value Valuation
APRE is unprofitable, so we... subscribe to Premium to read more.
Below Benjamin Graham Formula Value Valuation
There are 30 more APRE due diligence checks available for Premium users.

Valuation

APRE fair value

Fair Value of APRE stock based on Discounted Cash Flow (DCF)

Price
$0.78
Fair Value
$2.23
Undervalued by
65.07%
APRE ($0.78) is undervalued by... subscribe to Premium to read more.
Below Fair Value Valuation
APRE ($0.78) is significantly undervalued... subscribe to Premium to read more.
Significantly Below Fair Value Valuation
APRE is unprofitable, so we... subscribe to Premium to read more.
Below Benjamin Graham Formula Value Valuation

APRE price to earnings (PE)

For valuing profitable companies with steady earnings

Company
-0.75x
Industry
8.25x
Market
43.6x

APRE price to book (PB)

For valuing companies that are loss-making or have lots of physical asset

Company
0.26x
Industry
5.35x
APRE is good value based... subscribe to Premium to read more.
P/B vs Industry Valuation

APRE's financial health

Profit margin

Revenue
$0.0
Net Income
-$3.6M
Profit Margin
0%
APRE's cash burn is expected... subscribe to Premium to read more.
Interest Coverage Financials
APRE's profit margin has decreased... subscribe to Premium to read more.
Profit Margin Growth Financials

Assets to liabilities

Assets
$42.3M
Liabilities
$3.8M
Debt to equity
0.1
APRE's short-term assets ($41.91M) exceed... subscribe to Premium to read more.
Short-term Liabilities Financials
APRE's short-term assets ($41.91M) exceed... subscribe to Premium to read more.
Long-term Liabilities Financials
APRE's debt relative to shareholder... subscribe to Premium to read more.
Shrinking Debt Financials
APRE's debt to equity ratio... subscribe to Premium to read more.
Healthy Debt to Equity Financials

Cash flow

Operating
-$3.3M
Investing
$0.0
Financing
-$1.9M
APRE's cash and short-term investments... subscribe to Premium to read more.
Debt Coverage Financials

APRE vs Biotech Stocks

TickerZen RatingMarket Cap1d %P/EP/B
APRE$9.83M+0.90%-0.75x0.26x
LNAI$9.84M-8.82%-0.04x-1.03x
GDTC$10.08M+8.95%-3.20x1.97x
XBIO$10.15M+11.03%-3.73x1.67x
SNTI$9.41M-1.31%-0.18x-2.77x

Aprea Therapeutics Stock FAQ

What is Aprea Therapeutics's quote symbol?

(NASDAQ: APRE) Aprea Therapeutics trades on the NASDAQ under the ticker symbol APRE. Aprea Therapeutics stock quotes can also be displayed as NASDAQ: APRE.

If you're new to stock investing, here's how to buy Aprea Therapeutics stock.

What is the 52 week high and low for Aprea Therapeutics (NASDAQ: APRE)?

(NASDAQ: APRE) Aprea Therapeutics's 52-week high was $1.69, and its 52-week low was $0.55. It is currently -53.79% from its 52-week high and 42.52% from its 52-week low.

How much is Aprea Therapeutics stock worth today?

(NASDAQ: APRE) Aprea Therapeutics currently has 12,591,136 outstanding shares. With Aprea Therapeutics stock trading at $0.78 per share, the total value of Aprea Therapeutics stock (market capitalization) is $9.83M.

Aprea Therapeutics stock was originally listed at a price of $410.00 in Oct 3, 2019. If you had invested in Aprea Therapeutics stock at $410.00, your return over the last 6 years would have been -99.81%, for an annualized return of -64.79% (not including any dividends or dividend reinvestments).

How much is Aprea Therapeutics's stock price per share?

(NASDAQ: APRE) Aprea Therapeutics stock price per share is $0.78 today (as of Sep 14, 2026).

What is Aprea Therapeutics's Market Cap?

(NASDAQ: APRE) Aprea Therapeutics's market cap is $9.83M, as of Sep 15, 2026.

Market cap (market capitalization) is the total market value of a publicly traded company's outstanding shares.

Aprea Therapeutics's market cap is calculated by multiplying APRE's current stock price of $0.78 by APRE's total outstanding shares of 12,591,136.
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