| Name | Role | Date | Shares | Price | Value |
|---|---|---|---|---|---|
| Carl Dambkowski | Chief Medical Officer | 2026-07-01 | 5,500 | $132.74 | $730.07kSell |
| Carl Dambkowski | Chief Medical Officer | 2026-07-01 | 4,125 | $22.86 | $94.30kBuy |
| Michael Thomas Henderson | Chief Executive Officer | 2026-06-22 | 80,000 | $132.54 | $10.60MSell |
| Carl Dambkowski | Chief Medical Officer | 2026-06-22 | 26,400 | $132.60 | $3.50MSell |
| Michael Thomas Henderson | Chief Executive Officer | 2026-06-10 | 1,577 | $85.19 | $134.34kSell |
| Michael Thomas Henderson | Chief Executive Officer | 2026-06-10 | 1,080 | $84.18 | $90.91kSell |
| Michael Thomas Henderson | Chief Executive Officer | 2026-06-10 | 7,654 | $82.78 | $633.60kSell |
| Michael Thomas Henderson | Chief Executive Officer | 2026-06-10 | 6,770 | $82.21 | $556.56kSell |
| Michael Thomas Henderson | Chief Executive Officer | 2026-06-10 | 614 | $86.89 | $53.35kSell |
| Michael Thomas Henderson | Chief Executive Officer | 2026-06-10 | 2,305 | $86.27 | $198.85kSell |
| Name | Hold | Shares | Value | Type |
|---|---|---|---|---|
| T Rowe Price Investment Management Inc | 13.66% | 10,300,984 | $1.37B | Institution |
| Fmr LLC | 12.29% | 9,262,291 | $1.23B | Institution |
| Venrock Adviser LLC | 11.27% | 8,493,321 | $1.13B | Institution |
| Wellington Management Group LLP | 5.80% | 4,375,703 | $581.57M | Institution |
| Blackrock Inc | 5.42% | 4,085,651 | $543.02M | Institution |
| Rtw Investments LP | 3.69% | 2,782,097 | $369.77M | Institution |
| Vanguard Capital Management LLC | 3.32% | 2,502,095 | $332.55M | Institution |
| Janus Henderson Group PLC | 3.13% | 2,360,596 | $313.75M | Institution |
| State Street Corp | 2.87% | 2,162,964 | $287.48M | Institution |
| Driehaus Capital Management LLC | 2.55% | 1,920,800 | $255.29M | Institution |