| Name | Role | Date | Shares | Price | Value |
|---|---|---|---|---|---|
| Michael Thomas Henderson | Chief Executive Officer | 2026-05-13 | 18,659 | $82.05 | $1.53MSell |
| Michael Thomas Henderson | Chief Executive Officer | 2026-05-13 | 1,341 | $82.58 | $110.74kSell |
| Carl Dambkowski | Chief Medical Officer | 2026-05-06 | 3,700 | $83.92 | $310.50kSell |
| Carl Dambkowski | Chief Medical Officer | 2026-05-06 | 1,800 | $84.60 | $152.28kSell |
| Carl Dambkowski | Chief Medical Officer | 2026-05-06 | 4,125 | $22.86 | $94.30kBuy |
| Jane Henderson | Chief Financial Officer | 2026-05-01 | 900 | $82.60 | $74.34kSell |
| Jane Henderson | Chief Financial Officer | 2026-05-01 | 289 | $83.16 | $24.03kSell |
| Jane Henderson | Chief Financial Officer | 2026-05-01 | 811 | $81.02 | $65.71kSell |
| Jane Henderson | Chief Financial Officer | 2026-04-16 | 2,000 | $90.00 | $180.00kSell |
| Michael Thomas Henderson | Chief Executive Officer | 2026-04-16 | 3,000 | $22.86 | $68.58kBuy |
| Name | Hold | Shares | Value | Type |
|---|---|---|---|---|
| T Rowe Price Investment Management Inc | 13.66% | 10,300,984 | $811.20M | Institution |
| Fmr LLC | 12.29% | 9,262,291 | $729.41M | Institution |
| Venrock Adviser LLC | 11.27% | 8,493,321 | $668.85M | Institution |
| Wellington Management Group LLP | 5.80% | 4,375,703 | $344.59M | Institution |
| Blackrock Inc | 5.42% | 4,085,651 | $321.75M | Institution |
| Rtw Investments LP | 3.69% | 2,782,097 | $219.09M | Institution |
| Vanguard Capital Management LLC | 3.32% | 2,502,095 | $197.04M | Institution |
| Janus Henderson Group PLC | 3.13% | 2,360,596 | $185.90M | Institution |
| State Street Corp | 2.87% | 2,162,964 | $170.33M | Institution |
| Driehaus Capital Management LLC | 2.55% | 1,920,800 | $151.26M | Institution |