| Name | Role | Date | Shares | Price | Value |
|---|---|---|---|---|---|
| Carl Dambkowski | Chief Medical Officer | 2026-04-01 | 100 | $85.89 | $8.59kSell |
| Carl Dambkowski | Chief Medical Officer | 2026-04-01 | 2,698 | $84.31 | $227.47kSell |
| Carl Dambkowski | Chief Medical Officer | 2026-04-01 | 2,702 | $85.33 | $230.56kSell |
| Jane Henderson | Chief Financial Officer | 2026-04-01 | 1,100 | $85.46 | $94.01kSell |
| Jane Henderson | Chief Financial Officer | 2026-04-01 | 900 | $84.46 | $76.01kSell |
| Carl Dambkowski | Chief Medical Officer | 2026-04-01 | 4,125 | $22.86 | $94.30kBuy |
| Jane Henderson | Chief Financial Officer | 2026-03-25 | 2,000 | $85.00 | $170.00kSell |
| Michael Thomas Henderson | Chief Executive Officer | 2026-03-11 | 3,418 | $75.86 | $259.29kSell |
| Michael Thomas Henderson | Chief Executive Officer | 2026-03-11 | 8,219 | $74.83 | $615.03kSell |
| Michael Thomas Henderson | Chief Executive Officer | 2026-03-11 | 8,363 | $74.29 | $621.29kSell |
| Name | Hold | Shares | Value | Type |
|---|---|---|---|---|
| Vr Adviser LLC | 12.22% | 8,493,321 | $716.33M | Institution |
| Fmr LLC | 11.84% | 8,225,038 | $693.70M | Institution |
| Wellington Management Group LLP | 6.83% | 4,746,585 | $400.33M | Institution |
| Blackrock Inc | 5.45% | 3,783,994 | $319.14M | Institution |
| Vanguard Group Inc | 4.11% | 2,857,824 | $241.03M | Institution |
| T Rowe Price Investment Management Inc | 3.93% | 2,732,456 | $230.46M | Institution |
| Rtw Investments LP | 3.90% | 2,712,097 | $228.74M | Institution |
| Perceptive Advisors LLC | 3.35% | 2,330,651 | $196.57M | Institution |
| Driehaus Capital Management LLC | 3.14% | 2,183,704 | $184.17M | Institution |
| Janus Henderson Group PLC | 2.97% | 2,062,604 | $173.96M | Institution |