| Name | Role | Date | Shares | Price | Value |
|---|---|---|---|---|---|
| Andrew Cheng | President and CEO | 2025-10-10 | 30,000 | $53.98 | $1.62MSell |
| Andrew Cheng | President and CEO | 2025-10-10 | 30,000 | $19.87 | $596.10kBuy |
| G. Walmsley Graham | Director | 2025-10-08 | 23,832 | $19.97 | $475.93kBuy |
| Andrew Cheng | President and CEO | 2025-10-08 | 52,212 | $0.62 | $32.11kBuy |
| G. Walmsley Graham | Director | 2025-10-08 | 13,000 | $25.20 | $327.60kBuy |
| G. Walmsley Graham | Director | 2025-10-08 | 13,000 | $26.32 | $342.16kBuy |
| G. Walmsley Graham | Director | 2025-10-08 | 15,000 | $8.13 | $121.95kBuy |
| G. Walmsley Graham | Director | 2025-10-08 | 26,000 | $23.02 | $598.52kBuy |
| Timothy Rolph | Chief Scientific Officer | 2025-10-07 | 12,500 | $28.35 | $354.38kBuy |
| Timothy Rolph | Chief Scientific Officer | 2025-10-07 | 1,037 | $46.82 | $48.55kSell |
| Name | Hold | Shares | Value | Type |
|---|---|---|---|---|
| Versant Venture Capital VI LP | 8.47% | 6,749,283 | $365.81M | Insider |
| Janus Henderson Group PLC | 8.45% | 6,738,556 | $365.23M | Institution |
| Apple Tree Partners IV LP | 7.31% | 5,830,203 | $316.00M | Insider |
| Blackrock Inc | 7.25% | 5,779,412 | $313.24M | Institution |
| General Atlantic LP | 7.19% | 5,733,989 | $310.78M | Institution |
| Rtw Investments LP | 6.87% | 5,477,561 | $296.88M | Institution |
| Vanguard Group Inc | 5.68% | 4,529,628 | $245.51M | Institution |
| Price T Rowe Associates Inc | 5.66% | 4,509,325 | $244.41M | Institution |
| Aaron Royston | 4.96% | 3,954,858 | $214.35M | Insider |
| Avoro Capital Advisors LLC | 4.39% | 3,500,000 | $189.70M | Institution |