| Name | Role | Date | Shares | Price | Value | 
|---|---|---|---|---|---|
| Matthias Bodenstedt | Chief Financial Officer | 2025-10-08 | 10,870 | $9.09 | $98.81kBuy | 
| Bihua Chen | Insider | 2025-09-30 | 5,827 | $6.96 | $40.56kSell | 
| Bihua Chen | Insider | 2025-09-29 | 232,460 | $8.40 | $1.95MSell | 
| Bihua Chen | Insider | 2025-09-29 | 2,800,000 | $6.61 | $18.51MSell | 
| Bihua Chen | Insider | 2025-09-29 | 3,390,943 | $7.58 | $25.70MSell | 
| Bihua Chen | Insider | 2025-09-29 | 70,748 | $9.38 | $663.62kSell | 
| Catherine Moukheibir | Director | 2025-07-03 | 23,500 | $48.79 | $1.15MSell | 
| Name | Hold | Shares | Value | Type | 
|---|---|---|---|---|
| Bvf Inc | 30.75% | 19,751,284 | $189.81M | Institution | 
| Cormorant Asset Management LP | 13.22% | 8,494,151 | $81.63M | Institution | 
| Fmr LLC | 8.92% | 5,730,549 | $55.07M | Institution | 
| Bihua Chen | 7.54% | 4,844,173 | $46.55M | Insider | 
| Avoro Capital Advisors LLC | 6.46% | 4,150,000 | $39.88M | Institution | 
| Helix Holdings LLC | 5.01% | 3,215,000 | $30.90M | Insider | 
| Da Silva Jorge Santos | 4.79% | 3,078,577 | $29.59M | Insider | 
| Kristian Reich | 4.69% | 3,009,940 | $28.93M | Insider | 
| Price T Rowe Associates Inc | 4.07% | 2,613,233 | $25.11M | Institution | 
| Citadel Advisors LLC | 2.61% | 1,674,041 | $16.09M | Institution |