Best Biotech Stocks to Buy Now (2025)Top biotech stocks in 2025 ranked by overall Zen Rating. "A" Rated stocks have returned an average of +32.52% per year, and are the best biotech stocks to buy now. Learn More.
Industry: Biotechnology
F
Biotech is Zen Rated F and is the 138th ranked industry out of 145 stock market industries
Learn how the Zen Ratings work| Ticker | Company | Price | 1d % | 1w % | 1m % | 3m % | 6m % | 1y % | 3y % | 5y % | 10y % | 52-week High | 52-week Low | % off 52-week High | % off 52-week Low | Beta | Volume | Vol 1d % |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| TBPH | THERAVANCE BIOPHARMA INC | $14.40 | 0.70% | 3.45% | 9.51% | 33.95% | 54.01% | 77.34% | 43.28% | -19.24% | 7.46% | $14.55 | $7.88 | 1.03% | 82.74% | 0.64 | 448,000 | -47.23% |
| RIGL | RIGEL PHARMACEUTICALS INC | $37.30 | -1.74% | -8.74% | -5.59% | 82.57% | 77.37% | 171.27% | 182.58% | 51.01% | 12.01% | $43.72 | $13.37 | 14.68% | 178.98% | 1.32 | 743,000 | 95.53% |
| BCRX | BIOCRYST PHARMACEUTICALS INC | $7.70 | -2.65% | -5.98% | -8.00% | -25.17% | -0.52% | -2.65% | -39.98% | 92.50% | -41.22% | $11.31 | $6.02 | 31.92% | 28.01% | 1.22 | 3,124,000 | -2.31% |
| HALO | HALOZYME THERAPEUTICS INC | $76.33 | -0.74% | 0.63% | 13.47% | 41.56% | 21.25% | 21.33% | 80.32% | 177.26% | 318.02% | $77.60 | $42.01 | 1.64% | 81.69% | 0.86 | 1,277,000 | 13.92% |
| AUPH | AURINIA PHARMACEUTICALS INC | $12.81 | 0.55% | 4.15% | 4.40% | 57.37% | 52.50% | 79.66% | 69.00% | -14.08% | 275.66% | $12.90 | $6.55 | 0.70% | 95.57% | 1.09 | 1,177,000 | -14.02% |
| BMRN | BIOMARIN PHARMACEUTICAL INC | $53.14 | -1.76% | -5.75% | -7.65% | -5.51% | -25.73% | -23.93% | -39.68% | -29.63% | -59.71% | $73.51 | $52.93 | 27.71% | 0.40% | 0.74 | 1,829,000 | -5.23% |
| MDXG | MIMEDX GROUP INC | $6.97 | 0.43% | -2.79% | -1.97% | 16.36% | -13.31% | 12.06% | 102.62% | 11.52% | -32.59% | $10.14 | $5.47 | 31.26% | 27.42% | 1.23 | 393,000 | -5.98% |
| PBYI | PUMA BIOTECHNOLOGY INC | $4.64 | 3.80% | 1.75% | -19.02% | 34.49% | 43.21% | 84.13% | 81.25% | -53.55% | -95.45% | $6.07 | $2.32 | 23.56% | 100.00% | 1.00 | 456,000 | 20.95% |
| CRMD | CORMEDIX INC | $12.65 | -2.24% | -0.78% | -2.17% | -11.79% | 20.82% | 79.18% | 262.46% | 176.81% | -10.60% | $17.43 | $5.60 | 27.42% | 125.89% | 1.01 | 2,330,000 | 37.63% |
| KNSA | KINIKSA PHARMACEUTICALS INTERNATIONAL PLC | $36.56 | -1.46% | -0.03% | 9.53% | 28.69% | 59.16% | 45.31% | 249.19% | 110.84% | N/A | $37.34 | $17.82 | 2.09% | 105.16% | 0.86 | 562,000 | 41.92% |
| MIRM | MIRUM PHARMACEUTICALS INC | $74.19 | -0.16% | -4.13% | 9.22% | 47.14% | 64.32% | 83.55% | 223.69% | 250.95% | N/A | $78.10 | $36.86 | 5.00% | 101.28% | 0.75 | 436,000 | 29.76% |
| INVA | INNOVIVA INC | $19.55 | 0.93% | -4.45% | -6.55% | -10.32% | 11.52% | -2.45% | 56.90% | 74.55% | 92.99% | $22.00 | $16.67 | 11.14% | 17.28% | 0.46 | 768,000 | 23.08% |
| NAGE | NIAGEN BIOSCIENCE INC | $9.68 | 0.73% | 2.43% | -3.39% | -31.54% | 21.91% | 183.04% | 558.50% | 111.35% | 135.52% | $14.69 | $3.18 | 34.10% | 204.40% | 1.30 | 675,000 | -20.77% |
| GMAB | GENMAB A | $27.99 | 0.61% | 1.63% | 20.08% | 22.44% | 34.57% | 5.30% | -23.15% | -24.41% | 186.49% | $28.75 | $17.24 | 2.63% | 62.40% | 0.73 | 1,541,000 | 3.84% |
| AKBA | AKEBIA THERAPEUTICS INC | $2.92 | -1.02% | -6.71% | -10.15% | -18.44% | 21.67% | 108.57% | 689.19% | 10.61% | -72.40% | $4.08 | $1.24 | 28.41% | 135.48% | 1.50 | 2,490,000 | 10.47% |
| ONC | BEONE MEDICINES LTD | $332.27 | 2.44% | -4.09% | 3.39% | 25.66% | 25.35% | 69.14% | 106.85% | 30.08% | N/A | $351.27 | $170.99 | 5.41% | 94.32% | 0.96 | 356,000 | 29.45% |
| XERS | XERIS BIOPHARMA HOLDINGS INC | $7.36 | -1.74% | -5.28% | -4.17% | 67.27% | 46.32% | 155.56% | 311.17% | 32.61% | N/A | $8.03 | $2.69 | 8.34% | 173.61% | 1.20 | 1,454,000 | -13.45% |
| INCY | INCYTE CORP | $83.14 | 0.05% | -3.95% | -4.35% | 16.74% | 34.08% | 25.19% | 20.53% | -9.07% | -36.76% | $87.99 | $53.56 | 5.51% | 55.23% | 0.58 | 1,741,000 | -1.92% |
| LGND | LIGAND PHARMACEUTICALS INC | $165.52 | -0.14% | -0.21% | 9.55% | 43.91% | 50.54% | 57.63% | 83.64% | 72.43% | 70.25% | $169.49 | $93.58 | 2.35% | 76.87% | 1.12 | 266,000 | -11.04% |
| XOMA | XOMA ROYALTY CORP | $37.86 | 1.18% | 7.10% | 20.69% | 56.00% | 82.63% | 32.38% | 107.22% | 82.37% | 118.64% | $38.00 | $18.35 | 0.37% | 106.30% | 0.87 | 27,000 | -5.92% |
| TVTX | TRAVERE THERAPEUTICS INC | $23.01 | -1.96% | 8.54% | 22.26% | 56.74% | 10.25% | 61.25% | -15.40% | 17.88% | -19.46% | $28.69 | $12.91 | 19.81% | 78.23% | 1.09 | 2,223,000 | -24.46% |
| ZYME | ZYMEWORKS INC | $15.93 | 1.21% | 4.87% | 10.93% | 25.93% | 26.63% | 27.34% | 195.00% | -61.12% | N/A | $17.70 | $9.03 | 10.00% | 76.41% | 0.97 | 380,000 | 12.76% |
| ARQT | ARCUTIS BIOTHERAPEUTICS INC | $16.93 | -2.08% | -2.31% | 0.24% | 26.34% | 3.11% | 66.63% | -9.42% | -32.50% | N/A | $18.15 | $8.03 | 6.72% | 110.83% | 1.22 | 1,169,000 | -16.92% |
| SLGL | SOL-GEL TECHNOLOGIES LTD | $23.98 | -3.35% | -12.96% | 55.31% | 240.63% | 320.85% | 274.69% | -58.75% | -68.24% | N/A | $30.00 | $4.01 | 20.07% | 498.60% | 0.55 | 6,600 | -50.00% |
| ALNY | ALNYLAM PHARMACEUTICALS INC | $461.14 | -1.02% | 1.34% | 2.72% | 49.34% | 82.19% | 70.56% | 121.19% | 253.34% | 327.97% | $484.21 | $205.87 | 4.76% | 124.00% | 0.93 | 907,000 | 53.73% |
| VRTX | VERTEX PHARMACEUTICALS INC | $393.21 | -0.33% | -0.52% | 0.11% | -12.80% | -23.46% | -19.66% | 36.69% | 47.35% | 190.30% | $519.88 | $362.50 | 24.37% | 8.47% | 0.58 | 1,405,000 | 43.66% |
| DOMH | DOMINARI HOLDINGS INC | $5.93 | -9.60% | -2.63% | -7.34% | 18.13% | 21.02% | 212.11% | -7.20% | -40.26% | -99.23% | $13.58 | $0.83 | 56.33% | 617.92% | 1.19 | 345,000 | 69.95% |
| IONS | IONIS PHARMACEUTICALS INC | $61.10 | -3.26% | 0.16% | 39.56% | 73.38% | 78.13% | 50.12% | 28.66% | 15.44% | 10.73% | $64.72 | $23.95 | 5.59% | 155.11% | 0.85 | 2,151,000 | 46.23% |
| ABUS | ARBUTUS BIOPHARMA CORP | $4.53 | 1.57% | 10.76% | 34.62% | 26.54% | 38.11% | 6.34% | 96.10% | 54.08% | -35.01% | $5.10 | $2.71 | 11.18% | 67.47% | 0.97 | 968,000 | -42.72% |
| VCYT | VERACYTE INC | $31.87 | 3.21% | -1.82% | 5.46% | 19.63% | 2.05% | -5.23% | 62.60% | -1.24% | 254.11% | $47.32 | $22.61 | 32.64% | 40.96% | 1.95 | 712,000 | 15.77% |
| IMAB | I-MAB | $3.62 | -11.49% | -15.22% | -25.67% | 43.65% | 325.88% | 241.51% | -33.21% | -90.47% | N/A | $5.90 | $0.60 | 38.64% | 508.40% | 1.21 | 1,642,000 | 19.42% |
| CPRX | CATALYST PHARMACEUTICALS INC | $19.76 | -1.05% | -1.59% | -2.32% | -16.52% | -9.40% | -3.33% | 45.08% | 488.10% | 378.45% | $26.58 | $19.15 | 25.66% | 3.19% | 1.06 | 1,773,000 | 69.18% |
| FBIO | FORTRESS BIOTECH INC | $3.55 | -8.74% | -1.39% | 67.45% | 92.93% | 102.86% | 82.99% | -77.02% | -94.52% | -91.95% | $3.97 | $1.33 | 10.58% | 167.92% | 1.17 | 986,000 | 35.63% |
| HRMY | HARMONY BIOSCIENCES HOLDINGS INC | $32.50 | 0.34% | -9.29% | -11.85% | -1.22% | -5.30% | -16.15% | -27.68% | -8.71% | N/A | $41.61 | $26.47 | 21.89% | 22.78% | 0.86 | 808,000 | -0.25% |
| FHTX | FOGHORN THERAPEUTICS INC | $4.99 | -3.85% | -13.22% | 0.20% | 13.67% | 8.48% | -46.11% | -49.75% | N/A | N/A | $10.25 | $2.95 | 51.32% | 69.44% | 1.49 | 99,000 | 20.73% |
| LXRX | LEXICON PHARMACEUTICALS INC | $1.12 | -2.61% | 3.70% | -9.68% | 67.16% | 191.67% | -31.29% | -58.21% | -29.56% | -92.01% | $2.18 | $0.28 | 48.51% | 294.37% | 1.41 | 1,715,000 | 1.60% |
| CORT | CORCEPT THERAPEUTICS INC | $69.53 | -4.58% | -2.39% | -3.09% | -1.93% | 20.13% | 80.74% | 174.82% | 292.38% | 1,290.60% | $117.33 | $38.68 | 40.74% | 79.76% | 0.87 | 702,000 | 5.56% |
| FENC | FENNEC PHARMACEUTICALS INC | $8.67 | -1.03% | -3.88% | 3.71% | 6.12% | 37.18% | 66.73% | 29.02% | 42.13% | 327.09% | $9.42 | $3.96 | 7.96% | 118.94% | 0.69 | 37,700 | -5.75% |
| FOLD | AMICUS THERAPEUTICS INC | $7.73 | -3.25% | -3.13% | 4.46% | 27.77% | -15.24% | -30.11% | -29.41% | -44.43% | -57.60% | $12.65 | $5.51 | 38.89% | 40.29% | 1.02 | 3,394,000 | 17.93% |
| ACAD | ACADIA PHARMACEUTICALS INC | $24.67 | 4.49% | -2.84% | -2.61% | 11.43% | 43.43% | 52.85% | 35.03% | -36.40% | -41.55% | $26.65 | $13.40 | 7.43% | 84.10% | 0.91 | 2,783,000 | 80.71% |
| ZVRA | ZEVRA THERAPEUTICS INC | $7.23 | -6.71% | -13.21% | -23.33% | -20.77% | -13.41% | -7.07% | 5.55% | -35.54% | -97.98% | $13.16 | $6.19 | 45.06% | 16.80% | 0.84 | 1,300,000 | -28.34% |
| EXEL | EXELIXIS INC | $39.01 | -0.36% | 3.50% | 1.83% | -6.56% | 5.38% | 42.01% | 127.73% | 55.23% | 528.18% | $49.62 | $25.17 | 21.38% | 54.96% | 0.63 | 2,334,000 | -5.74% |
| ASND | ASCENDIS PHARMA A | $194.62 | -0.49% | -5.17% | -1.87% | 9.52% | 15.27% | 39.44% | 78.08% | 36.58% | 886.42% | $208.16 | $118.03 | 6.50% | 64.89% | 0.73 | 225,000 | -0.88% |
| VCEL | VERICEL CORP | $31.42 | -2.36% | -5.42% | -13.40% | -24.45% | -33.99% | -29.74% | 20.15% | 73.40% | 872.76% | $63.00 | $30.26 | 50.13% | 3.83% | 1.50 | 1,222,000 | 49.21% |
| RPRX | ROYALTY PHARMA PLC | $35.15 | -3.33% | -1.82% | -3.30% | 0.14% | 6.45% | 24.38% | -16.65% | -13.65% | N/A | $38.00 | $24.05 | 7.50% | 46.15% | 0.52 | 4,694,000 | 28.50% |
| JAZZ | JAZZ PHARMACEUTICALS PLC | $125.22 | -0.75% | -3.57% | 6.33% | 14.21% | -10.70% | 14.28% | -17.72% | -11.51% | -22.35% | $148.06 | $95.49 | 15.42% | 31.13% | 0.73 | 581,000 | 3.75% |
| ARGX | ARGENX SE | $756.83 | 0.06% | -1.45% | 15.75% | 37.30% | 23.22% | 40.69% | 99.07% | 224.43% | N/A | $779.03 | $510.06 | 2.85% | 48.38% | 0.66 | 364,000 | 7.37% |
| TGTX | TG THERAPEUTICS INC | $31.75 | -1.27% | -1.95% | 13.07% | -10.89% | -22.67% | 27.56% | 334.93% | 25.84% | 169.75% | $46.48 | $21.16 | 31.69% | 50.05% | 1.90 | 1,907,000 | -20.08% |
| ATRA | ATARA BIOTHERAPEUTICS INC | $11.94 | -1.49% | -1.97% | -2.85% | 39.16% | 66.53% | 38.84% | -89.84% | -96.95% | -98.95% | $18.71 | $5.01 | 36.17% | 138.56% | 1.89 | 31,500 | -16.00% |
| OVID | OVID THERAPEUTICS INC | $1.28 | 1.59% | 3.23% | 31.96% | 339.86% | 174.68% | 9.40% | -41.55% | -80.03% | N/A | $1.47 | $0.24 | 12.93% | 428.93% | 0.89 | 876,000 | 41.75% |
| TECH | BIO-TECHNE CORP | $51.62 | 0.70% | -4.60% | -3.69% | -0.02% | -17.51% | -30.95% | -34.74% | -15.93% | 113.51% | $80.95 | $46.01 | 36.23% | 12.19% | 1.18 | 1,927,000 | -0.82% |
| VALN | VALNEVA SE | $8.93 | -0.11% | 4.81% | -22.55% | 47.12% | 27.99% | 42.02% | -47.69% | N/A | N/A | $12.25 | $3.62 | 27.10% | 146.69% | 1.06 | 76,500 | 91.25% |
| PTCT | PTC THERAPEUTICS INC | $58.98 | -3.45% | 3.56% | 20.81% | 13.71% | 3.17% | 74.65% | 9.93% | 23.93% | 58.80% | $62.18 | $33.88 | 5.15% | 74.09% | 1.00 | 1,301,000 | -26.04% |
| MDGL | MADRIGAL PHARMACEUTICALS INC | $425.60 | -1.53% | -6.21% | 15.08% | 49.30% | 24.28% | 82.36% | 511.49% | 298.05% | 504.98% | $457.16 | $200.63 | 6.90% | 112.13% | 0.78 | 265,000 | 38.74% |
| ASMB | ASSEMBLY BIOSCIENCES INC | $21.19 | -3.02% | -9.13% | -16.71% | 22.91% | 100.09% | 15.48% | -15.51% | -90.06% | -87.01% | $27.17 | $7.75 | 22.02% | 173.42% | 0.89 | 79,000 | 17.91% |
| FTRE | FORTREA HOLDINGS INC | $10.20 | 0.99% | -1.16% | 26.87% | 76.17% | 2.20% | -52.97% | N/A | N/A | N/A | $25.28 | $3.97 | 59.65% | 156.93% | 1.58 | 1,236,000 | -16.66% |
| SPRO | SPERO THERAPEUTICS INC | $1.88 | -1.05% | -5.76% | -1.57% | -34.04% | 143.84% | 37.23% | 93.81% | -81.18% | N/A | $3.22 | $0.51 | 41.61% | 272.28% | 0.77 | 305,000 | -21.99% |
| MESO | MESOBLAST LTD | $15.46 | 4.32% | 6.25% | -4.86% | 25.69% | 17.21% | 151.38% | 142.32% | -56.33% | N/A | $22.00 | $6.00 | 29.73% | 157.67% | 1.28 | 163,000 | -12.37% |
| NTHI | NEONC TECHNOLOGIES HOLDINGS INC | $9.97 | -4.96% | 20.70% | 94.73% | 75.53% | N/A | N/A | N/A | N/A | N/A | $25.00 | $3.20 | 60.12% | 211.56% | -1.29 | 109,000 | -43.23% |
| ADPT | ADAPTIVE BIOTECHNOLOGIES CORP | $13.08 | 3.73% | 4.31% | 0.31% | 27.11% | 73.47% | 184.97% | 54.98% | -71.53% | N/A | $13.68 | $3.98 | 4.39% | 228.56% | 2.00 | 1,462,000 | -25.03% |
| APLS | APELLIS PHARMACEUTICALS INC | $24.39 | -1.85% | -9.36% | -12.11% | 33.28% | -2.87% | -32.83% | -62.33% | -21.83% | N/A | $37.84 | $16.10 | 35.54% | 51.49% | 1.02 | 3,169,000 | 87.51% |
| REGN | REGENERON PHARMACEUTICALS INC | $572.59 | 2.25% | 2.53% | -1.35% | 9.55% | -15.60% | -50.34% | -18.88% | -1.26% | 5.75% | $1.17k | $476.49 | 50.89% | 20.17% | 0.62 | 996,000 | 65.17% |
| IMCR | IMMUNOCORE HOLDINGS PLC | $34.42 | -2.33% | -6.06% | 4.68% | 4.59% | 14.58% | 4.30% | -23.63% | N/A | N/A | $39.33 | $23.15 | 12.48% | 48.68% | 0.74 | 137,000 | -25.95% |
| PLX | PROTALIX BIOTHERAPEUTICS INC | $1.91 | 5.52% | 20.89% | 29.05% | 33.57% | -22.04% | 75.23% | 63.25% | -45.74% | -86.36% | $3.10 | $0.99 | 38.39% | 92.93% | 0.66 | 1,351,000 | 48.79% |
| EVAX | EVAXION A | $2.92 | -0.85% | -1.02% | 1.39% | 21.67% | 56.15% | -82.03% | -97.17% | N/A | N/A | $16.69 | $1.20 | 82.50% | 143.33% | 0.60 | 24,800 | -36.08% |
| INBX | INHIBRX BIOSCIENCES INC | $27.19 | -1.22% | -6.58% | 16.52% | 85.94% | 95.01% | 55.97% | N/A | N/A | N/A | $30.23 | $10.81 | 10.07% | 151.60% | 0.97 | 80,000 | -27.93% |
| RCUS | ARCUS BIOSCIENCES INC | $11.58 | 0.52% | 1.22% | 11.45% | 27.39% | 26.56% | -31.48% | -56.89% | -45.40% | N/A | $18.98 | $6.50 | 38.99% | 78.15% | 1.53 | 585,000 | -4.41% |
| BDTX | BLACK DIAMOND THERAPEUTICS INC | $3.19 | -1.85% | 4.59% | 15.58% | 33.47% | 86.55% | -41.14% | 21.76% | -89.05% | N/A | $5.69 | $1.20 | 43.94% | 166.95% | 1.53 | 908,000 | -18.86% |
| GYRE | GYRE THERAPEUTICS INC | $7.90 | 0.89% | 0.13% | -2.95% | -1.62% | -35.67% | -43.81% | -73.27% | -89.05% | -99.63% | $19.00 | $6.11 | 58.42% | 29.30% | 1.27 | 55,600 | -25.87% |
| ZYBT | ZHENGYE BIOTECHNOLOGY HOLDING LTD | $10.69 | 14.70% | 31.17% | 42.34% | 48.89% | 130.89% | N/A | N/A | N/A | N/A | $14.30 | $3.50 | 25.24% | 205.43% | 1.42 | 229,000 | -21.31% |
| BNTX | BIONTECH SE | $97.88 | 1.18% | -4.66% | -13.78% | -7.95% | -2.95% | -20.73% | -32.09% | 46.26% | N/A | $131.49 | $81.20 | 25.56% | 20.54% | 0.95 | 1,410,000 | -72.64% |
| KRYS | KRYSTAL BIOTECH INC | $155.71 | 8.37% | 7.24% | 3.62% | 17.04% | -16.68% | -19.85% | 118.42% | 236.96% | N/A | $207.84 | $122.80 | 25.08% | 26.80% | 1.36 | 798,000 | 127.35% |
| SRPT | SAREPTA THERAPEUTICS INC | $17.47 | 0.46% | -0.74% | -19.90% | -16.57% | -82.76% | -85.95% | -84.22% | -87.77% | -54.21% | $138.81 | $10.42 | 87.41% | 67.74% | 0.89 | 5,132,000 | 46.34% |
| ABEO | ABEONA THERAPEUTICS INC | $5.73 | -10.96% | -14.55% | -19.71% | -4.02% | 8.02% | 7.41% | 40.66% | -88.61% | -95.59% | $7.54 | $3.93 | 24.07% | 45.56% | 0.77 | 2,218,000 | 89.41% |
| AAPG | ASCENTAGE PHARMA GROUP INTERNATIONAL | $38.63 | -4.52% | -5.87% | -14.15% | 20.23% | 96.29% | N/A | N/A | N/A | N/A | $48.45 | $17.00 | 20.27% | 127.24% | 0.49 | 10,900 | 12.37% |
| AXSM | AXSOME THERAPEUTICS INC | $116.78 | -1.39% | -9.68% | 6.92% | 14.83% | -7.09% | 26.37% | 89.29% | 43.71% | N/A | $139.13 | $75.56 | 16.07% | 54.55% | 0.95 | 421,000 | -38.18% |
| IRD | OPUS GENETICS INC | $1.37 | -0.72% | -2.14% | 14.17% | 45.59% | 45.44% | 5.38% | -40.43% | -82.44% | -99.47% | $1.75 | $0.65 | 21.71% | 110.77% | 0.87 | 149,000 | -54.29% |
| VRCA | VERRICA PHARMACEUTICALS INC | $4.94 | 4.00% | -2.37% | -17.11% | -25.04% | -24.06% | -73.86% | -87.00% | -94.49% | N/A | $20.01 | $3.82 | 75.31% | 29.45% | 0.92 | 85,000 | 388.51% |
| TARS | TARSUS PHARMACEUTICALS INC | $49.59 | 0.47% | -12.83% | -8.52% | 20.10% | 4.42% | 55.55% | 210.52% | N/A | N/A | $59.76 | $30.23 | 17.02% | 64.07% | 0.89 | 867,000 | -29.28% |
| OKYO | OKYO PHARMA LTD | $2.09 | -2.79% | -5.43% | -21.13% | -18.36% | 40.27% | 100.00% | -32.03% | N/A | N/A | $3.35 | $0.90 | 37.59% | 131.71% | 0.40 | 55,600 | 35.61% |
| SLNO | SOLENO THERAPEUTICS INC | $51.17 | -4.57% | -29.23% | -28.56% | -34.52% | 3.10% | -3.07% | 2,280.00% | 60.91% | -75.63% | $90.32 | $41.50 | 43.35% | 23.30% | 0.52 | 2,282,000 | -29.78% |
| PTHS | PELTHOS THERAPEUTICS INC | $33.00 | 1.57% | 2.61% | 57.44% | 170.49% | 96.43% | 288.24% | N/A | N/A | N/A | $54.29 | $4.50 | 39.22% | 633.33% | 1.22 | 8,300 | -12.63% |
| KZIA | KAZIA THERAPEUTICS LTD | $7.99 | -0.13% | -1.36% | -0.56% | -11.71% | 59.80% | -53.00% | -88.83% | -97.78% | -98.36% | $39.05 | $2.86 | 79.54% | 179.37% | 0.97 | 32,800 | -60.95% |
| ENTA | ENANTA PHARMACEUTICALS INC | $7.46 | -9.90% | -16.27% | -6.75% | 2.47% | 22.30% | -36.83% | -87.12% | -84.05% | -82.28% | $13.37 | $4.09 | 44.20% | 82.40% | 0.94 | 401,000 | 79.02% |
| MNKD | MANNKIND CORP | $5.38 | -3.41% | -3.41% | 44.24% | 41.21% | 2.67% | -17.86% | 43.85% | 203.95% | -70.11% | $7.63 | $3.38 | 29.49% | 59.12% | 1.12 | 6,169,000 | 48.29% |
| NVO | NOVO NORDISK A S | $55.62 | 1.37% | 2.47% | 6.12% | -27.78% | -30.61% | -59.37% | 7.78% | 63.78% | 98.22% | $135.20 | $45.05 | 58.86% | 23.46% | 0.61 | 13,724,000 | 33.20% |
| CVAC | CUREVAC NV | $5.36 | 0.37% | 0.19% | -2.19% | -2.90% | 74.59% | 63.91% | -44.40% | -90.05% | N/A | $5.72 | $2.37 | 6.29% | 126.16% | 1.20 | 365,000 | -70.06% |
| RARE | ULTRAGENYX PHARMACEUTICAL INC | $29.00 | -4.32% | -7.97% | -2.32% | -21.85% | -26.84% | -51.15% | -38.66% | -64.30% | -76.57% | $59.90 | $25.81 | 51.59% | 12.36% | 1.09 | 1,994,000 | 43.35% |
| ARWR | ARROWHEAD PHARMACEUTICALS INC | $28.67 | -3.53% | 5.52% | 39.79% | 82.61% | 83.78% | 40.20% | -18.39% | -15.18% | 309.57% | $31.13 | $9.57 | 7.90% | 199.58% | 1.61 | 2,227,000 | -26.86% |
| CDTX | CIDARA THERAPEUTICS INC | $66.91 | 1.97% | 7.66% | 2.60% | 198.57% | 200.45% | 467.03% | 363.82% | 2.31% | -77.80% | $69.36 | $10.14 | 3.53% | 559.86% | 0.79 | 1,177,000 | 210.55% |
| MAZE | MAZE THERAPEUTICS INC | $23.25 | -0.19% | 55.31% | 72.22% | 74.68% | 102.35% | N/A | N/A | N/A | N/A | $25.50 | $6.71 | 8.82% | 246.50% | 0.90 | 556,000 | -56.12% |
| TCRX | TSCAN THERAPEUTICS INC | $1.69 | -3.98% | -10.11% | -6.11% | 10.46% | 9.03% | -70.56% | -48.16% | N/A | N/A | $6.23 | $1.02 | 72.85% | 65.69% | 0.75 | 308,000 | 33.91% |
| PGEN | PRECIGEN INC | $3.59 | -5.28% | -13.70% | 22.11% | 133.12% | 101.69% | 259.00% | 31.50% | -32.07% | -92.19% | $5.23 | $0.65 | 31.29% | 451.46% | 1.74 | 6,605,000 | 22.45% |
| ZLAB | ZAI LAB LTD | $31.92 | -2.68% | 1.88% | -10.66% | -21.44% | -16.77% | 54.35% | -34.79% | -59.49% | N/A | $44.34 | $20.17 | 28.01% | 58.25% | 1.28 | 489,000 | -48.90% |
| GERN | GERON CORP | $1.27 | 0.00% | -7.30% | -12.41% | -18.06% | -27.01% | -70.94% | -56.21% | -31.35% | -64.23% | $4.83 | $1.09 | 73.68% | 16.51% | 1.13 | 4,283,000 | 0.66% |
| NRSN | NEUROSENSE THERAPEUTICS LTD | $1.16 | -4.92% | 0.00% | -2.52% | -52.65% | -1.36% | -13.43% | -43.96% | N/A | N/A | $2.60 | $0.80 | 55.38% | 45.00% | 0.58 | 551,000 | -74.12% |
| UTHR | UNITED THERAPEUTICS CORP | $403.11 | -0.47% | 2.15% | 28.74% | 39.70% | 24.83% | 16.85% | 82.70% | 281.19% | 160.22% | $436.95 | $266.98 | 7.74% | 50.99% | 0.44 | 695,000 | 11.02% |
| MNPR | MONOPAR THERAPEUTICS | $54.49 | 10.71% | 31.36% | 52.59% | 59.23% | 59.19% | 1,200.48% | 568.59% | 95.30% | N/A | $54.54 | $3.90 | 0.09% | 1,297.18% | 0.70 | 43,300 | 93.30% |
| NAMS | NEWAMSTERDAM PHARMA CO NV | $24.12 | -0.29% | -3.87% | -3.79% | 22.13% | 3.34% | 52.27% | 142.17% | N/A | N/A | $27.35 | $14.06 | 11.81% | 71.55% | 0.43 | 1,038,000 | -12.33% |
| LIXT | LIXTE BIOTECHNOLOGY HOLDINGS INC | $5.70 | -5.08% | 31.79% | 58.77% | 413.51% | 367.21% | 179.41% | -19.24% | -43.00% | 119.23% | $6.26 | $0.64 | 8.95% | 790.63% | 0.41 | 209,000 | -36.67% |
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