| Name | Role | Date | Shares | Price | Value |
|---|---|---|---|---|---|
| Shawn McCormick | Director | 2025-12-02 | 1,200 | $139.00 | $166.80kSell |
| Shawn McCormick | Director | 2025-11-28 | 2,000 | $127.48 | $254.96kSell |
| Shelley G. Broader | Director | 2025-10-14 | 245 | $78.84 | $19.32kBuy |
| Georgia Melenikiotou | Director | 2025-10-14 | 229 | $78.84 | $18.05kBuy |
| Casey M. Tansey | Director | 2025-10-14 | 221 | $78.84 | $17.42kBuy |
| Gary Lee Ellis | Director | 2025-10-14 | 372 | $78.84 | $29.33kBuy |
| Richard Buchholz | Chief Financial Officer | 2025-08-29 | 11,000 | $93.39 | $1.03MSell |
| Richard Buchholz | Chief Financial Officer | 2025-08-19 | 7,159 | $42.15 | $301.75kBuy |
| Richard Buchholz | Chief Financial Officer | 2025-08-19 | 17,849 | $71.00 | $1.27MBuy |
| Richard Buchholz | Chief Financial Officer | 2025-08-19 | 2,649 | $90.24 | $239.05kSell |
| Name | Hold | Shares | Value | Type |
|---|---|---|---|---|
| Blackrock Inc | 12.21% | 3,547,195 | $510.76M | Institution |
| Presidio Management Group IX LLC | 11.56% | 3,359,107 | $483.68M | Insider |
| Vanguard Group Inc | 10.33% | 3,000,087 | $431.98M | Institution |
| Orbimed Advisors LLC | 8.42% | 2,446,005 | $352.20M | Insider |
| Mudit K. Jain | 7.22% | 2,096,810 | $301.92M | Insider |
| Synergy Life Science Partners L P | 7.21% | 2,095,507 | $301.73M | Insider |
| Kleiner Perkins Caufield Byers XII LLC | 6.67% | 1,937,244 | $278.94M | Insider |
| Citadel Advisors LLC | 6.02% | 1,748,409 | $251.75M | Institution |
| Amzak Health Investors LLC | 5.15% | 1,497,043 | $215.56M | Insider |
| William Blair Investment Management LLC | 4.47% | 1,297,573 | $186.84M | Institution |