| Name | Role | Date | Shares | Price | Value |
|---|---|---|---|---|---|
| Carlton Weatherby | Chief Strategy and Growth Officer. | 2026-02-20 | 672 | $59.53 | $40.00kSell |
| Timothy P. Herbert | CEO and President | 2026-02-20 | 4,010 | $59.53 | $238.72kSell |
| Bryan K. Phillips | Senior Vice President General Counsel Secretary and Chief Compliance Officer. | 2026-02-20 | 735 | $59.53 | $43.75kSell |
| John Rondoni | Title Chief Product and Innovation Officer. | 2026-02-20 | 735 | $59.53 | $43.75kSell |
| John Rondoni | Title Chief Product and Innovation Officer.Exhibit 24 - Power of Attorney. | 2026-02-13 | 587 | $59.76 | $35.08kSell |
| Carlton Weatherby | Chief Strategy and Growth Officer. Exhibit 24 - Power of Attorney. | 2026-02-13 | 570 | $59.76 | $34.06kSell |
| Richard Buchholz | Interim CFO | 2026-02-13 | 579 | $59.76 | $34.60kSell |
| Timothy P. Herbert | CEO and President | 2026-02-13 | 1,635 | $59.76 | $97.71kSell |
| Bryan K. Phillips | Officer | 2026-02-13 | 579 | $59.76 | $34.60kSell |
| Jason P. Kelly | Title - Chief Manufacturing and Quality Officer.Exhibit 24 - Power of Attorney. | 2026-02-13 | 551 | $59.76 | $32.93kSell |
| Name | Hold | Shares | Value | Type |
|---|---|---|---|---|
| Blackrock Inc | 12.42% | 3,550,848 | $185.21M | Institution |
| Presidio Management Group IX LLC | 11.75% | 3,359,107 | $175.21M | Insider |
| Vanguard Group Inc | 10.33% | 2,953,170 | $154.04M | Institution |
| Orbimed Advisors LLC | 8.56% | 2,446,005 | $127.58M | Insider |
| Wellington Management Group LLP | 7.73% | 2,211,091 | $115.33M | Institution |
| Mudit K. Jain | 7.33% | 2,096,810 | $109.37M | Insider |
| Synergy Life Science Partners L P | 7.33% | 2,095,507 | $109.30M | Insider |
| Kleiner Perkins Caufield Byers XII LLC | 6.78% | 1,937,244 | $101.05M | Insider |
| Deerfield Management Company LP | 5.27% | 1,505,872 | $78.55M | Institution |
| Amzak Health Investors LLC | 5.24% | 1,497,043 | $78.09M | Insider |