| Name | Role | Date | Shares | Price | Value |
|---|---|---|---|---|---|
| John E. Davis | Chief Commercial Officer | 2025-12-15 | 5,000 | $45.11 | $225.55kSell |
| Amy Horton | VP Chief Accounting Officer | 2025-12-08 | 4,572 | $44.42 | $203.08kSell |
| Jean F. Holloway | SVP General Counsel | 2025-12-03 | 5,267 | $45.30 | $238.60kSell |
| James P. MacKin | President CEO | 2025-12-03 | 30,921 | $29.62 | $915.88kBuy |
| James P. MacKin | President CEO | 2025-12-03 | 30,921 | $45.46 | $1.41MSell |
| Jean F. Holloway | SVP General Counsel | 2025-12-03 | 2,048 | $45.30 | $92.77kSell |
| James P. MacKin | President CEO | 2025-12-02 | 30,921 | $45.56 | $1.41MSell |
| James P. MacKin | President CEO | 2025-12-02 | 30,921 | $29.62 | $915.88kBuy |
| Marshall S. Stanton | SVP Clinical MD Affair | 2025-11-21 | 18,705 | $44.91 | $840.04kSell |
| Marshall S. Stanton | SVP Clinical MD Affair | 2025-11-21 | 27,075 | $11.03 | $298.64kBuy |
| Name | Hold | Shares | Value | Type |
|---|---|---|---|---|
| Blackrock Inc | 12.77% | 6,049,645 | $281.61M | Institution |
| Oss Capital Management | 8.27% | 3,918,000 | $182.38M | Insider |
| Vanguard Group Inc | 6.39% | 3,029,059 | $141.00M | Institution |
| Fmr LLC | 6.31% | 2,988,161 | $139.10M | Institution |
| Macquarie Group Ltd | 5.24% | 2,483,842 | $115.62M | Institution |
| Morgan Stanley | 4.73% | 2,238,494 | $104.20M | Institution |
| Perceptive Advisors LLC | 4.26% | 2,020,000 | $94.03M | Institution |
| Steven G. Anderson | 3.52% | 1,668,370 | $77.66M | Insider |
| State Street Corp | 3.25% | 1,540,279 | $71.70M | Institution |
| Wellington Management Group LLP | 3.17% | 1,501,085 | $69.88M | Institution |