| Name | Role | Date | Shares | Price | Value |
|---|---|---|---|---|---|
| David T. Howton | Chief Operating Officer | 2025-12-03 | 4,932 | $5.11 | $25.20kSell |
| Jessie Hanrahan | Chief Regulatory Officer | 2025-12-03 | 4,483 | $5.11 | $22.91kSell |
| Alexander Cumbo | President and CEO | 2025-12-03 | 10,808 | $5.11 | $55.23kSell |
| Paul Herzich | Chief Technology Officer | 2025-12-03 | 2,701 | $5.11 | $13.80kSell |
| Ilan Ganot | Director | 2025-11-10 | 3,278 | $4.12 | $13.51kSell |
| Gabriel Brooks | Chief Medical Officer | 2025-10-20 | 2,895 | $5.96 | $17.25kSell |
| Clare Kahn | Director | 2025-03-11 | 1,860 | $5.34 | $9.92kBuy |
| Perceptive Advisors LLC | Director | 2025-02-19 | 5,000,000 | $4.03 | $20.15MBuy |
| Bain Capital Life Sciences Investors LLC | 10% Owner | 2025-02-19 | 1,000,000 | $4.03 | $4.03MBuy |
| Adage Capital Management LP | 10% Owner | 2025-02-18 | 252,545 | $7.56 | $1.91MBuy |
| Name | Hold | Shares | Value | Type |
|---|---|---|---|---|
| Rajeev M. Shah | 17.05% | 13,281,046 | $77.96M | Insider |
| Perceptive Advisors LLC | 15.19% | 11,833,539 | $69.46M | Institution |
| Ra Capital Management LP | 15.00% | 11,689,948 | $68.62M | Insider |
| Bain Capital Life Sciences Investors LLC | 10.15% | 7,911,669 | $46.44M | Institution |
| Ultragenyx Pharmaceutical Inc | 10.04% | 7,825,797 | $45.94M | Insider |
| Siren LLC | 9.52% | 7,415,905 | $43.53M | Institution |
| Ra Capital Management LP | 7.46% | 5,811,423 | $34.11M | Institution |
| Gilad David Hayeem | 6.59% | 5,136,501 | $30.15M | Insider |
| Bain Capital Life Sciences Investors LLC | 6.46% | 5,034,582 | $29.55M | Insider |
| Blackrock Inc | 6.06% | 4,725,118 | $27.74M | Institution |