| Name | Hold | Shares | Value | Type |
|---|---|---|---|---|
| Adage Capital Partners GP LLC | 5.81% | 6,253,467 | $9.76M | Institution |
| Privium Fund Management Bv | 5.08% | 5,467,149 | $8.53M | Institution |
| Aberdeen Group PLC | 3.08% | 3,316,965 | $5.17M | Institution |
| Affinity Asset Advisors LLC | 2.28% | 2,454,278 | $3.83M | Institution |
| Sio Capital Management LLC | 1.81% | 1,954,715 | $3.05M | Institution |
| Dafna Capital Management LLC | 1.46% | 1,567,561 | $2.45M | Institution |
| Kynam Capital Management LP | 1.45% | 1,566,317 | $2.44M | Institution |
| Ikarian Capital LLC | 1.39% | 1,492,229 | $2.33M | Institution |
| Morgan Stanley | 1.21% | 1,299,775 | $2.03M | Institution |
| Platinum Investment Management Ltd | 1.15% | 1,235,514 | $1.93M | Institution |