| Name | Hold | Shares | Value | Type |
|---|---|---|---|---|
| Adage Capital Partners GP LLC | 5.94% | 6,253,467 | $11.01M | Institution |
| Privium Fund Management Bv | 5.09% | 5,357,762 | $9.43M | Institution |
| Aberdeen Group PLC | 2.80% | 2,950,676 | $5.19M | Institution |
| Affinity Asset Advisors LLC | 2.33% | 2,454,278 | $4.32M | Institution |
| Sio Capital Management LLC | 2.05% | 2,164,181 | $3.81M | Institution |
| Dafna Capital Management LLC | 1.49% | 1,567,561 | $2.76M | Institution |
| Kynam Capital Management LP | 1.49% | 1,566,317 | $2.76M | Institution |
| Ikarian Capital LLC | 1.42% | 1,492,229 | $2.63M | Institution |
| Morgan Stanley | 1.30% | 1,367,119 | $2.41M | Institution |
| Platinum Investment Management Ltd | 1.17% | 1,235,514 | $2.17M | Institution |