| Name | Hold | Shares | Value | Type |
|---|---|---|---|---|
| Aberdeen Group PLC | 60.52% | 8,243,941 | $117.06M | Institution |
| Bvf Inc | 56.18% | 7,652,972 | $108.67M | Institution |
| Avidity Partners Management LP | 54.10% | 7,369,352 | $104.64M | Institution |
| Muneer A. Satter | 52.36% | 7,132,277 | $101.28M | Insider |
| Vanguard Capital Management LLC | 37.72% | 5,138,316 | $72.96M | Institution |
| Soleus Capital Management LP | 33.04% | 4,500,000 | $63.90M | Institution |
| Laurion Capital Management LP | 28.50% | 3,882,162 | $55.13M | Institution |
| Millennium Management LLC | 27.75% | 3,779,922 | $53.67M | Institution |
| Morgan Stanley | 24.14% | 3,288,540 | $46.70M | Institution |
| Nantahala Capital Management LLC | 18.40% | 2,506,491 | $35.59M | Institution |