| Name | Hold | Shares | Value | Type |
|---|---|---|---|---|
| Alan L. Crane | 33.93% | 4,848,940 | $8.15M | Insider |
| Polaris Venture Management Co V LLC | 22.83% | 3,262,437 | $5.48M | Insider |
| Venrock Associates V LP | 21.10% | 3,015,017 | $5.07M | Insider |
| Cvf LLC | 18.14% | 2,592,577 | $4.36M | Insider |
| Lilly Co Eli | 16.49% | 2,356,227 | $3.96M | Insider |
| Steven Edward Hall | 16.49% | 2,356,227 | $3.96M | Insider |
| Roger Hawley | 11.02% | 1,575,367 | $2.65M | Insider |
| Polaris Venture Management Co IV LLC | 10.02% | 1,432,101 | $2.41M | Insider |
| Sabrina Martucci Johnson | 6.73% | 962,062 | $1.62M | Insider |
| Lux Capital Management LLC | 6.66% | 951,999 | $1.60M | Insider |