| Name | Hold | Shares | Value | Type |
|---|---|---|---|---|
| Alan L. Crane | 32.37% | 4,848,940 | $10.04M | Insider |
| Polaris Venture Management Co V LLC | 21.78% | 3,262,437 | $6.75M | Insider |
| Venrock Associates V LP | 20.13% | 3,015,017 | $6.24M | Insider |
| Cvf LLC | 17.31% | 2,592,577 | $5.37M | Insider |
| Steven Edward Hall | 15.73% | 2,356,227 | $4.88M | Insider |
| Lilly Co Eli | 15.73% | 2,356,227 | $4.88M | Insider |
| Roger Hawley | 10.52% | 1,575,367 | $3.26M | Insider |
| Polaris Venture Management Co IV LLC | 9.56% | 1,432,101 | $2.96M | Insider |
| Sabrina Martucci Johnson | 6.42% | 962,062 | $1.99M | Insider |
| Lux Capital Management LLC | 6.36% | 951,999 | $1.97M | Insider |