| Name | Hold | Shares | Value | Type |
|---|---|---|---|---|
| Alan L. Crane | 33.30% | 4,848,940 | $13.33M | Insider |
| Polaris Venture Management Co V LLC | 22.41% | 3,262,437 | $8.97M | Insider |
| Venrock Associates V LP | 20.71% | 3,015,017 | $8.29M | Insider |
| Cvf LLC | 17.81% | 2,592,577 | $7.13M | Insider |
| Lilly Co Eli | 16.18% | 2,356,227 | $6.48M | Insider |
| Steven Edward Hall | 16.18% | 2,356,227 | $6.48M | Insider |
| Roger Hawley | 10.82% | 1,575,367 | $4.33M | Insider |
| Polaris Venture Management Co IV LLC | 9.84% | 1,432,101 | $3.94M | Insider |
| Sabrina Martucci Johnson | 6.61% | 962,062 | $2.65M | Insider |
| Lux Capital Management LLC | 6.54% | 951,999 | $2.62M | Insider |