| Name | Role | Date | Shares | Price | Value |
|---|---|---|---|---|---|
| David Dalvey | Director | 2026-01-27 | 20,000 | $120.03 | $2.40MSell |
| Richard E. Buller | Director | 2025-12-05 | 3,000 | $5.50 | $16.50kBuy |
| Richard E. Buller | Director | 2025-12-05 | 1,490 | $105.34 | $156.96kSell |
| Richard E. Buller | Director | 2025-12-05 | 1,510 | $106.04 | $160.11kSell |
| Leo Furcht | Director | 2025-12-04 | 250 | $7.60 | $1.90kBuy |
| Richard E. Buller | Director | 2025-12-01 | 1,100 | $14.83 | $16.31kBuy |
| Richard E. Buller | Director | 2025-12-01 | 1,100 | $98.14 | $107.95kSell |
| David Dalvey | Director | 2025-11-21 | 15,000 | $100.00 | $1.50MSell |
| Richard E. Buller | Director | 2025-11-20 | 3,900 | $14.83 | $57.84kBuy |
| Richard E. Buller | Director | 2025-11-20 | 3,900 | $96.73 | $377.25kSell |
| Name | Hold | Shares | Value | Type |
|---|---|---|---|---|
| Baker Bros Advisors LP | 17.11% | 7,915,792 | $881.34M | Institution |
| Baker Bros Advisors LP | 15.59% | 7,211,484 | $802.93M | Insider |
| Brian F. Sullivan | 6.74% | 3,120,983 | $347.49M | Insider |
| Perceptive Advisors LLC | 6.39% | 2,956,319 | $329.16M | Institution |
| Blackrock Inc | 4.85% | 2,246,447 | $250.12M | Institution |
| Nea Management Company LLC | 4.63% | 2,144,261 | $238.74M | Institution |
| Vanguard Group Inc | 4.45% | 2,059,047 | $229.25M | Institution |
| Morgan Stanley | 3.27% | 1,512,852 | $168.44M | Institution |
| Lance G. Laing | 2.70% | 1,250,000 | $139.18M | Insider |
| Soleus Capital Management LP | 2.55% | 1,178,860 | $131.25M | Institution |