| Name | Role | Date | Shares | Price | Value |
|---|---|---|---|---|---|
| Fairmount Funds Management LLC | Director | 2026-07-16 | 853,450 | $14.50 | $12.38MBuy |
| Joshua T. Brumm | Chief Executive Officer | 2026-06-22 | 42,305 | $17.99 | $761.07kSell |
| Richard William Scalzo | Chief Financial Officer | 2026-06-22 | 1,112 | $17.99 | $20.00kSell |
| Barbara Harlin Bispham | General Counsel and Corporate Secretary. | 2026-06-22 | 1,218 | $17.99 | $21.91kSell |
| Ellie Eunkyung Im | Chief Medical Officer | 2026-06-22 | 1,219 | $17.99 | $21.93kSell |
| Ryan Lynch | Treasurer Senior Vice President of Finance and Chief Accounting Officer. | 2026-06-22 | 465 | $17.99 | $8.37kSell |
| Jonathan McNeill | President and COO | 2026-06-22 | 20,549 | $17.99 | $369.68kSell |
| Jan Pinkas | Chief Scientific Officer | 2026-06-22 | 1,288 | $17.99 | $23.17kSell |
| Fairmount Funds Management LLC | Director | 2025-12-04 | 1,360,000 | $13.41 | $18.24MBuy |
| Name | Hold | Shares | Value | Type |
|---|---|---|---|---|
| Scott D. Sandell | 37.84% | 14,056,571 | $234.60M | Insider |
| M. James Barrett | 35.49% | 13,182,418 | $220.01M | Insider |
| Peter J. Barris | 35.49% | 13,182,418 | $220.01M | Insider |
| Siren LLC | 23.12% | 8,589,064 | $143.35M | Insider |
| Fairmount Funds Management LLC | 17.09% | 6,349,182 | $105.97M | Insider |
| Invus Public Equities LP | 17.01% | 6,317,565 | $105.44M | Insider |
| New Enterprise Associates 10 L P | 13.45% | 4,995,664 | $83.38M | Insider |
| New Enterprise Associates 13 LP | 11.02% | 4,093,377 | $68.32M | Insider |
| Sanofi | 3.21% | 1,193,625 | $19.92M | Insider |
| Michael A. Henos | 2.68% | 995,395 | $16.61M | Insider |