| Name | Role | Date | Shares | Price | Value |
|---|---|---|---|---|---|
| Gina Mazzariello | Chief Legal Officer | 2026-07-10 | 15,000 | $17.61 | $264.12kSell |
| Gina Mazzariello | Chief Legal Officer | 2026-07-09 | 15,000 | $18.32 | $274.74kSell |
| Karen Firestone | Director | 2026-05-21 | 3,800 | $13.51 | $51.34kBuy |
| James M. Frates | Chief Financial Officer | 2026-03-02 | 7,909 | $14.52 | $114.85kSell |
| Camille L. Bedrosian | Chief Medical Officer | 2026-03-02 | 6,461 | $14.58 | $94.21kSell |
| Joshua B. Cohen | Co-Chief Executive Officer | 2026-03-02 | 29,282 | $14.48 | $424.12kSell |
| Justin B. Klee | Co-Chief Executive Officer | 2026-03-02 | 29,282 | $14.47 | $423.77kSell |
| Gina Mazzariello | Chief Legal Officer | 2026-03-02 | 6,844 | $14.52 | $99.38kSell |
| Gina Mazzariello | Chief Legal Officer | 2026-02-23 | 3,419 | $14.14 | $48.35kSell |
| Joshua B. Cohen | Co-Chief Executive Officer | 2026-02-02 | 15,500 | $14.68 | $227.59kSell |
| Name | Hold | Shares | Value | Type |
|---|---|---|---|---|
| Morningside Venture Investments Ltd | 23.47% | 26,091,760 | $631.16M | Insider |
| Fmr LLC | 14.96% | 16,630,541 | $402.29M | Institution |
| Isaac Cheng | 9.37% | 10,422,228 | $252.11M | Insider |
| Blackrock Inc | 7.94% | 8,828,836 | $213.57M | Institution |
| Perceptive Advisors LLC | 7.45% | 8,284,882 | $200.41M | Institution |
| Tcg Crossover Management LLC | 5.62% | 6,243,812 | $151.04M | Institution |
| Invest 1. Bv Als | 5.30% | 5,895,280 | $142.61M | Insider |
| Commodore Capital LP | 5.08% | 5,650,000 | $136.67M | Institution |
| Janus Henderson Group PLC | 4.48% | 4,986,073 | $120.61M | Institution |
| Saturn V Capital Management LP | 3.91% | 4,349,885 | $105.22M | Institution |