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Best Biotech Stocks to Buy Now (2025)
Top biotech stocks in 2025 ranked by overall Zen Rating. "A" Rated stocks have returned an average of +32.52% per year, and are the best biotech stocks to buy now. Learn More.

Industry: Biotechnology

Value Growth Financials Momentum Sentiment Forecast Dividends Due Diligence

Biotech is Zen Rated F and is the 137th ranked industry out of 145 stock market industries

Ticker	Company	Price	1d %	1w %	1m %	3m %	6m %	1y %	3y %	5y %	10y %	52-week High	52-week Low	% off 52-week High	% off 52-week Low	Beta	Volume	Vol 1d %
PBM	PSYENCE BIOMEDICAL LTD	$0.44	-3.51%	-4.76%	-25.68%	-69.86%	-91.55%	-99.51%	-99.94%	N/A	N/A	$108.00	$0.37	99.59%	19.89%	0.30	533,221	212.27%
APVO	APTEVO THERAPEUTICS INC	$0.50	-5.85%	-27.89%	-50.00%	-88.53%	-94.56%	-98.60%	-99.99%	-99.99%	N/A	$44.03	$0.49	98.87%	1.84%	1.31	408,685	-56.10%
PPBT	PURPLE BIOTECH LTD	$2.35	-2.08%	-13.92%	-10.98%	-25.63%	-24.44%	-77.54%	-96.02%	-96.64%	N/A	$20.60	$2.00	88.59%	17.50%	0.84	87,387	-98.04%
ADAG	ADAGENE INC	$1.58	3.95%	13.67%	-12.95%	-17.28%	-47.33%	-32.19%	-56.47%	N/A	N/A	$3.58	$1.33	55.88%	19.25%	0.30	15,705	-13.93%
XTLB	XTL BIOPHARMACEUTICALS LTD	$1.53	8.51%	17.69%	31.33%	-10.00%	-34.89%	-41.15%	-29.49%	31.90%	-86.03%	$3.15	$0.92	51.43%	66.12%	0.68	23,830	-73.17%
TCRT	ALAUNOS THERAPEUTICS INC	$2.24	-8.57%	-16.42%	3.70%	47.37%	9.80%	-82.64%	-96.97%	-99.41%	-99.84%	$14.20	$1.31	84.23%	70.47%	1.19	25,815	99.68%
THAR	THARIMMUNE INC	$1.55	-10.40%	28.63%	21.09%	-22.50%	-42.38%	-72.44%	-99.66%	N/A	N/A	$6.45	$0.95	75.96%	62.82%	0.72	314,260	-41.70%
TENX	TENAX THERAPEUTICS INC	$5.73	-0.52%	-0.69%	-9.91%	-3.70%	27.76%	46.92%	-99.47%	-99.43%	-99.99%	$7.89	$2.77	27.38%	106.86%	0.48	20,415	45.30%
IMNN	IMUNON INC	$0.84	0.00%	-6.25%	-20.38%	-3.45%	-11.58%	-35.88%	-72.64%	-95.45%	-99.85%	$3.65	$0.64	76.99%	31.25%	0.85	52,525	-38.36%
ASBP	ASPIRE BIOPHARMA HOLDINGS INC	$0.36	-15.33%	-29.33%	-37.89%	-96.58%	-96.85%	-96.78%	-96.42%	N/A	N/A	$15.80	$0.33	97.73%	8.79%	0.53	568,669	92.79%
VANI	VIVANI MEDICAL INC	$1.04	0.97%	0.97%	1.96%	-11.11%	-19.38%	-37.35%	-78.99%	-69.32%	-99.63%	$2.09	$0.91	50.24%	14.92%	1.16	21,792	0.93%
SPRO	SPERO THERAPEUTICS INC	$0.66	0.30%	-8.97%	-4.90%	-17.81%	-44.07%	-57.28%	-87.03%	-94.50%	N/A	$1.72	$0.51	61.63%	30.69%	0.81	27,448	-65.38%
KZIA	KAZIA THERAPEUTICS LTD	$3.93	9.47%	15.01%	-1.33%	-47.25%	-85.76%	-73.69%	-98.76%	-97.11%	-99.66%	$79.00	$2.86	95.03%	37.41%	0.98	65,925	-1.27%
OKYO	OKYO PHARMA LTD	$1.57	-1.26%	3.51%	32.63%	47.64%	30.42%	4.33%	N/A	N/A	N/A	$1.74	$0.81	10.06%	93.93%	0.52	291,781	636.23%
PALI	PALISADE BIO INC	$0.78	0.64%	6.11%	16.57%	-40.15%	-71.81%	-88.97%	-99.86%	-99.97%	-100.00%	$8.57	$0.60	90.89%	30.17%	1.07	47,580	-37.60%
TRAW	TRAWS PHARMA INC	$1.41	-2.76%	-7.84%	-34.11%	-81.17%	-71.75%	-91.45%	-95.91%	-98.78%	-100.00%	$19.44	$1.36	92.75%	3.68%	0.73	28,036	-12.69%
PYPD	POLYPID LTD	$2.80	-1.75%	5.07%	1.86%	-5.41%	-15.15%	-44.00%	-98.15%	N/A	N/A	$4.94	$2.30	43.32%	21.74%	0.66	12,773	-81.86%
TSBX	TURNSTONE BIOLOGICS CORP	$0.35	-4.93%	8.78%	-7.71%	-15.16%	-30.32%	-86.65%	N/A	N/A	N/A	$3.39	$0.29	89.76%	19.66%	1.19	87,685	218.38%
KLTO	KLOTHO NEUROSCIENCES INC	$0.18	10.30%	14.47%	-20.52%	-54.73%	-56.56%	-97.06%	-98.16%	N/A	N/A	$11.05	$0.11	98.35%	59.65%	0.49	647,432	1,178.12%
OVID	OVID THERAPEUTICS INC	$0.32	-3.67%	-6.53%	1.61%	-52.34%	-72.37%	-89.71%	-89.14%	-90.51%	N/A	$3.43	$0.24	90.81%	30.17%	0.84	318,038	-30.76%
SNGX	SOLIGENIX INC	$1.92	-2.54%	-10.90%	-13.12%	-15.79%	-50.26%	-69.70%	-98.53%	-99.48%	-99.95%	$14.83	$1.68	87.05%	14.29%	0.45	33,383	326.67%
SYBX	SYNLOGIC INC	$1.14	0.00%	-1.72%	-6.56%	-13.64%	-21.92%	-40.00%	-95.45%	-96.26%	N/A	$1.91	$0.90	40.31%	26.95%	0.87	109	-97.24%
SER	SERINA THERAPEUTICS INC	$5.31	-15.85%	-12.81%	-0.56%	8.15%	-22.72%	-40.34%	-82.56%	-81.36%	N/A	$14.57	$3.81	63.56%	39.37%	0.34	9,453	-49.46%
TOVX	THERIVA BIOLOGICS INC	$1.40	3.70%	-0.92%	25.00%	16.67%	-29.65%	-86.21%	-97.69%	-98.32%	-99.99%	$12.28	$0.96	88.60%	46.44%	0.83	23,045	-16.62%
PHGE	BIOMX INC	$0.58	-4.76%	-5.07%	17.65%	-21.09%	-20.33%	-86.95%	-95.77%	-98.96%	N/A	$4.90	$0.48	88.16%	21.59%	0.42	84,962	123.55%
TTNP	TITAN PHARMACEUTICALS INC	$3.85	3.22%	1.58%	-2.28%	16.67%	-3.87%	-42.54%	-72.43%	-97.43%	-99.97%	$14.80	$3.03	73.99%	27.06%	0.40	23,724	2,010.68%
SCNI	SCINAI IMMUNOTHERAPEUTICS LTD	$2.77	5.00%	14.46%	-1.42%	-21.28%	-22.19%	-36.99%	-98.02%	-99.80%	N/A	$8.92	$1.90	68.95%	45.79%	0.84	10,789	-90.90%
NBTX	NANOBIOTIX SA	$3.31	-2.36%	0.30%	-7.54%	-5.16%	-24.77%	-44.83%	-43.90%	N/A	N/A	$7.51	$2.76	55.93%	19.93%	0.95	19,707	-12.22%
SABS	SAB BIOTHERAPEUTICS INC	$1.70	0.00%	13.33%	38.21%	-20.93%	-56.19%	-58.54%	-92.92%	N/A	N/A	$5.01	$1.00	66.07%	70.00%	0.67	9,112	-48.33%
PHAR	PHARMING GROUP NV	$8.75	-0.28%	1.98%	1.47%	6.71%	2.70%	-16.27%	7.89%	N/A	N/A	$11.07	$6.65	20.96%	31.58%	0.50	2,394	11.04%
AEON	AEON BIOPHARMA INC	$0.44	0.92%	-5.00%	-26.43%	-95.33%	-99.31%	-99.83%	-99.94%	N/A	N/A	$269.28	$0.38	99.84%	16.53%	0.11	186,864	-10.20%
RLMD	RELMADA THERAPEUTICS INC	$0.35	8.70%	-52.51%	27.74%	2.94%	-89.97%	-90.51%	-98.65%	-99.11%	N/A	$4.47	$0.24	92.17%	45.83%	0.69	2,087,871	-9.38%
RGLS	REGULUS THERAPEUTICS INC	$7.85	-1.63%	180.36%	348.57%	538.21%	426.85%	212.75%	308.64%	61.86%	-99.51%	$8.20	$0.83	4.27%	845.78%	1.01	5,668,043	-80.16%
RNXT	RENOVORX INC	$0.99	3.13%	-1.98%	3.13%	-27.74%	-2.94%	-18.18%	-39.26%	N/A	N/A	$1.69	$0.75	41.42%	32.00%	0.87	112,646	58.40%
RENB	RENOVARO INC	$0.31	-14.17%	-17.16%	-38.32%	-59.50%	-42.46%	-78.98%	-96.21%	-90.31%	N/A	$2.34	$0.30	86.79%	1.64%	1.12	594,901	-27.27%
PTN	PALATIN TECHNOLOGIES INC	$0.17	-60.90%	-67.71%	-78.46%	-85.14%	-81.25%	-91.75%	-98.55%	-98.56%	-99.33%	$2.48	$0.16	93.35%	2.48%	1.19	6,504,308	535.06%
PMN	PROMIS NEUROSCIENCES INC	$0.65	4.84%	15.86%	-13.91%	-29.27%	-43.48%	-66.13%	N/A	N/A	N/A	$2.37	$0.51	72.57%	27.20%	0.35	15,218	14.22%
QLGN	QUALIGEN THERAPEUTICS INC	$3.52	-1.68%	-3.27%	0.86%	0.57%	-28.46%	-76.51%	-98.72%	-99.93%	N/A	$29.44	$2.85	88.04%	23.51%	0.70	7,553	-47.20%
PTIX	PROTAGENIC THERAPEUTICS INC	$0.24	8.48%	13.02%	-2.80%	-36.05%	-60.03%	-81.31%	-92.47%	-95.14%	-99.61%	$1.87	$0.18	87.01%	35.75%	-0.15	365,290	-48.32%
PRTC	PURETECH HEALTH PLC	$17.66	2.32%	3.03%	-7.54%	-9.44%	-15.22%	-36.68%	-11.85%	N/A	N/A	$32.98	$13.30	46.45%	32.78%	0.50	2,791	150.54%
PMCB	PHARMACYTE BIOTECH INC	$1.17	-5.65%	-3.31%	-9.30%	-25.95%	-36.07%	-45.07%	-48.91%	-96.85%	-99.51%	$2.42	$1.03	51.71%	13.59%	0.44	6,127	119.06%
PASG	PASSAGE BIO INC	$0.34	2.76%	3.08%	-13.21%	-41.64%	-46.74%	-75.19%	-82.55%	-98.13%	N/A	$1.64	$0.30	79.57%	11.67%	1.40	459,948	115.49%
VRCA	VERRICA PHARMACEUTICALS INC	$0.47	1.29%	0.64%	11.64%	-26.68%	-69.28%	-93.14%	-92.88%	-95.72%	N/A	$11.41	$0.38	95.88%	23.04%	0.92	128,855	7.60%
OGEN	ORAGENICS INC	$0.20	5.91%	1.55%	-7.08%	-32.30%	-33.67%	-80.69%	-98.98%	-99.35%	-99.96%	$3.43	$0.16	94.26%	21.60%	0.87	207,491	78.29%
RNTX	REIN THERAPEUTICS INC	$1.64	-4.09%	-10.38%	-6.29%	-14.58%	-59.00%	-60.58%	-80.62%	-83.56%	N/A	$4.40	$1.35	62.73%	21.48%	1.01	27,926	-16.71%
PLRZ	POLYRIZON LTD	$0.25	-18.39%	-27.51%	-30.68%	-79.43%	-78.38%	N/A	N/A	N/A	N/A	$4.80	$0.25	94.73%	2.43%	-1.24	477,889	220.10%
NRXS	NEURAXIS INC	$2.31	-1.70%	-3.14%	9.48%	-6.85%	-10.81%	-30.00%	N/A	N/A	N/A	$3.78	$1.33	38.89%	73.68%	0.92	3,273	-87.85%
NLSP	NLS PHARMACEUTICS LTD	$1.50	1.90%	0.00%	-2.60%	-30.88%	-58.33%	-71.99%	-95.13%	N/A	N/A	$18.39	$1.30	91.84%	15.38%	0.36	13,361	145.29%
TNFA	TNF PHARMACEUTICALS INC	$0.20	4.69%	4.69%	-54.52%	-72.39%	-84.89%	-93.72%	-99.82%	-99.91%	-100.00%	$3.37	$0.16	94.03%	24.07%	1.00	1,941,780	113.21%
NERV	MINERVA NEUROSCIENCES INC	$1.67	0.00%	-4.57%	7.74%	-25.94%	-36.26%	-30.42%	-58.24%	-97.78%	-95.87%	$3.69	$1.15	54.74%	45.22%	0.50	111	-99.41%
NCNA	NUCANA PLC	$0.52	-11.86%	-20.00%	-41.57%	-46.39%	-66.23%	-86.93%	-97.03%	-99.62%	N/A	$10.79	$0.52	95.18%	0.00%	0.95	263,568	-30.08%
ZYBT	ZHENGYE BIOTECHNOLOGY HOLDING LTD	$10.43	14.49%	-1.14%	96.05%	141.44%	N/A	N/A	N/A	N/A	N/A	$14.30	$3.50	27.06%	198.00%	1.39	423,871	4.01%
MTVA	METAVIA INC	$0.76	0.13%	-10.35%	-51.62%	-56.21%	-71.46%	-79.29%	-99.49%	-99.98%	N/A	$5.30	$0.65	85.62%	17.77%	0.46	52,557	-33.06%
MRSN	MERSANA THERAPEUTICS INC	$0.40	-7.62%	10.50%	19.76%	-29.20%	-78.02%	-88.13%	-89.19%	-95.14%	N/A	$3.63	$0.26	88.98%	54.44%	1.62	2,434,736	-26.20%
PCSA	PROCESSA PHARMACEUTICALS INC	$0.25	-3.10%	4.60%	-39.32%	-63.34%	-78.26%	-88.74%	-99.53%	-99.83%	-99.98%	$3.10	$0.15	91.94%	66.67%	0.76	3,517,039	-67.18%
MTNB	MATINAS BIOPHARMA HOLDINGS INC	$0.62	4.91%	4.20%	8.77%	8.01%	6.53%	-93.21%	-98.31%	-98.35%	N/A	$9.60	$0.48	93.54%	30.53%	1.02	51,783	-5.86%
NXTC	NEXTCURE INC	$0.48	3.23%	14.56%	9.84%	-37.82%	-63.91%	-64.96%	-88.26%	-98.57%	N/A	$1.82	$0.22	73.63%	114.29%	0.90	98,512	-60.07%
MLEC	MOOLEC SCIENCE SA	$0.75	1.22%	28.47%	33.75%	0.94%	-10.83%	-44.10%	-92.47%	N/A	N/A	$1.45	$0.53	48.34%	41.32%	0.38	47,408	23.53%
LYRA	LYRA THERAPEUTICS INC	$0.11	-5.88%	13.13%	-6.67%	-38.46%	-56.76%	-97.87%	-98.10%	-99.40%	N/A	$4.71	$0.08	97.62%	36.59%	0.45	896,668	-61.07%
SPRB	SPRUCE BIOSCIENCES INC	$0.08	5.06%	-36.15%	-71.38%	-77.51%	-85.93%	-88.31%	-95.28%	N/A	N/A	$0.87	$0.06	90.46%	45.61%	1.14	4,396,493	-66.56%
MEIP	MEI PHARMA INC	$2.05	0.49%	-4.87%	-4.65%	-25.72%	-33.22%	-33.01%	-81.32%	-96.12%	-94.85%	$4.10	$1.46	50.00%	40.41%	0.72	2,762	-66.72%

Biotech Stocks FAQ

What are the best biotech stocks to buy right now in May 2025?

According to Zen Ratings, our proprietary rating system that evaluates 115 factors proven to drive growth in stocks and assigns each stock in our system an overall letter grade as well as 7 individual Component Grades for Value, Growth, Momentum, Sentiment, Safety, Financials, and proprietary AI algorithms, the 3 best biotechnology stocks to buy right now are:

1. Protalix Biotherapeutics (NYSEMKT:PLX)

Protalix Biotherapeutics (NYSEMKT:PLX) is the #1 top biotech stock out of 661 with a Zen Rating of A. Stocks with a rating of A have had an average return of +32.52% per year. Learn more.

The Component Grade breakdown for Protalix Biotherapeutics (NYSEMKT:PLX) is: Value: B, Growth: A, Momentum: B, Sentiment: A, Safety: C, Financials: B, and AI: B.

Protalix Biotherapeutics (NYSEMKT:PLX) has a Due Diligence Score of 23, which is -1 points lower than the biotech industry average of 24. Although this number is below the industry average, our proven quant model rates PLX as a "A".

PLX passed 7 out of 33 due diligence checks and has weak fundamentals. Protalix Biotherapeutics has seen its stock return 147.93% over the past year, overperforming other biotech stocks by 225 percentage points.

Protalix Biotherapeutics has an average 1 year price target of $15.00, an upside of 400% from Protalix Biotherapeutics's current stock price of $3.00.

Protalix Biotherapeutics stock has a consensus Buy recommendation according to Wall Street analysts. Of the 1 analyst covering Protalix Biotherapeutics, 0% have issued a Strong Buy rating, 100% have issued a Buy, 0% have issued a hold, while 0% have issued a Sell rating, and 0% have issued a Strong Sell.

2. Aurinia Pharmaceuticals (NASDAQ:AUPH)

Aurinia Pharmaceuticals (NASDAQ:AUPH) is the #2 top biotech stock out of 661 with a Zen Rating of A. Stocks with a rating of A have had an average return of +32.52% per year. Learn more.

The Component Grade breakdown for Aurinia Pharmaceuticals (NASDAQ:AUPH) is: Value: B, Growth: A, Momentum: C, Sentiment: A, Safety: C, Financials: B, and AI: C.

Aurinia Pharmaceuticals (NASDAQ:AUPH) has a Due Diligence Score of 57, which is 33 points higher than the biotech industry average of 24.

AUPH passed 19 out of 33 due diligence checks and has strong fundamentals. Aurinia Pharmaceuticals has seen its stock return 57.69% over the past year, overperforming other biotech stocks by 135 percentage points.

3. Catalyst Pharmaceuticals (NASDAQ:CPRX)

Catalyst Pharmaceuticals (NASDAQ:CPRX) is the #3 top biotech stock out of 661 with a Zen Rating of A. Stocks with a rating of A have had an average return of +32.52% per year. Learn more.

The Component Grade breakdown for Catalyst Pharmaceuticals (NASDAQ:CPRX) is: Value: A, Growth: C, Momentum: C, Sentiment: A, Safety: D, Financials: A, and AI: B.

Catalyst Pharmaceuticals (NASDAQ:CPRX) has a Due Diligence Score of 76, which is 52 points higher than the biotech industry average of 24.

CPRX passed 25 out of 33 due diligence checks and has strong fundamentals. Catalyst Pharmaceuticals has seen its stock return 59.67% over the past year, overperforming other biotech stocks by 137 percentage points.

Catalyst Pharmaceuticals has an average 1 year price target of $33.20, an upside of 36.79% from Catalyst Pharmaceuticals's current stock price of $24.27.

Catalyst Pharmaceuticals stock has a consensus Strong Buy recommendation according to Wall Street analysts. Of the 5 analysts covering Catalyst Pharmaceuticals, 60% have issued a Strong Buy rating, 40% have issued a Buy, 0% have issued a hold, while 0% have issued a Sell rating, and 0% have issued a Strong Sell.

What are the biotech stocks with highest dividends?

Out of 5 biotech stocks that have issued dividends in the past year, the 3 biotech stocks with the highest dividend yields are:

1. Dominari Holdings (NASDAQ:DOMH)

Dominari Holdings (NASDAQ:DOMH) has an annual dividend yield of 6.27%, which is 4 percentage points higher than the biotech industry average of 1.81%.

Dominari Holdings's dividend payout ratio of -13.4% indicates that its high dividend yield might not be sustainable for the long-term.

2. Novo Nordisk (Ozempic) (NYSE:NVO)

Novo Nordisk (Ozempic) (NYSE:NVO) has an annual dividend yield of 2.46%, which is 1 percentage points higher than the biotech industry average of 1.81%. Novo Nordisk (Ozempic)'s dividend payout is not stable, having dropped more than 10% ten times in the last 10 years. Novo Nordisk (Ozempic)'s dividend has shown consistent growth over the last 10 years.

Novo Nordisk (Ozempic)'s dividend payout ratio of 45.5% indicates that its dividend yield is sustainable for the long-term.

3. Royalty Pharma (NASDAQ:RPRX)

Royalty Pharma (NASDAQ:RPRX) has an annual dividend yield of 1.32%, which is the same as the biotech industry average of 1.81%. Royalty Pharma's dividend payout is stable, having never dropped by more than 10% in the last 10 years. Royalty Pharma's dividend has shown consistent growth over the last 10 years.

Royalty Pharma's dividend payout ratio of 43.8% indicates that its dividend yield is sustainable for the long-term.

Why are biotech stocks down?

Biotech stocks were down -0.68% in the last day, and up 1.97% over the last week. Arvinas was the among the top losers in the biotechnology industry, dropping -24.84% yesterday.

Arvinas shares are trading lower. The company reported Q1 financial results.

What are the most undervalued biotech stocks?

Based on the Valuation rating, one of the 7 components of a stocks overall Zen Ratings grade, which evaluates factors including estimated earnings yield, earnings before interest and taxes/enterprise value, cash flow yield, free cash flow to price, and price-to-earnings growth (PEG ratio), the 3 most undervalued biotech stocks right now are:

1. Puma Biotechnology (NASDAQ:PBYI)

Puma Biotechnology (NASDAQ:PBYI) is the most undervalued biotech stock based on its Valuation Rating of A. Valuation is one of 7 Component Grades used to calculate the overall Zen Rating.

Puma Biotechnology has a valuation score of 43, which is 29 points higher than the biotech industry average of 14. It passed 3 out of 7 valuation due diligence checks.

Puma Biotechnology's stock has dropped -37.78% in the past year. It has overperformed other stocks in the biotech industry by 39 percentage points.

2. Harmony Biosciences Holdings (NASDAQ:HRMY)

Harmony Biosciences Holdings (NASDAQ:HRMY) is the second most undervalued biotech stock based on its Valuation Rating of A. Valuation is one of 7 Component Grades used to calculate the overall Zen Rating.

Harmony Biosciences Holdings has a valuation score of 71, which is 57 points higher than the biotech industry average of 14. It passed 5 out of 7 valuation due diligence checks.

Harmony Biosciences Holdings's stock has dropped -1.35% in the past year. It has overperformed other stocks in the biotech industry by 76 percentage points.

3. Jazz Pharmaceuticals (NASDAQ:JAZZ)

Jazz Pharmaceuticals (NASDAQ:JAZZ) is the third most undervalued biotech stock based on its Valuation Rating of A. Valuation is one of 7 Component Grades used to calculate the overall Zen Rating.

Jazz Pharmaceuticals has a valuation score of 71, which is 57 points higher than the biotech industry average of 14. It passed 5 out of 7 valuation due diligence checks.

Jazz Pharmaceuticals's stock has gained 6.23% in the past year. It has overperformed other stocks in the biotech industry by 83 percentage points.

Are biotech stocks a good buy now?

54.79% of biotech stocks rated by analysts are a strong buy right now. On average, analysts expect biotech stocks to rise by 102% over the next year.

1.74% of biotech stocks have a Zen Rating of A (Strong Buy), 4.13% of biotech stocks are rated B (Buy), 42.39% are rated C (Hold), 35.87% are rated D (Sell), and 15.87% are rated F (Strong Sell).

What is the average p/e ratio of the biotechnology industry?

The average P/E ratio of the biotechnology industry is -169.39x.

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