Sectors & IndustriesHealthcareBiotechnology
Best Biotech Stocks to Buy Now (2025)
Top biotech stocks in 2025 ranked by overall Zen Rating. "A" Rated stocks have returned an average of +32.52% per year, and are the best biotech stocks to buy now. Learn More.

Industry: Biotechnology
F
Biotech is Zen Rated F and is the 140th ranked industry out of 145 stock market industries
Learn how the Zen Ratings work
Ticker
Company
Zen Rating
Financials
Market Cap
ROE
ROA
ROCE
ROIC
D/E
Current Ratio
Gross Margin
Profit Margin
Operating Margin
UNCY
UNICYCIVE THERAPEUTICS INC
$82.15M-278.40%-61.80%-134.77%156.50%1.481.64N/AN/AN/A
ERAS
ERASCA INC
$419.27M-36.60%-31.10%-35.35%-36.10%0.1812.35N/AN/AN/A
ATAI
ATAI LIFE SCIENCES NV
$422.71M-102.40%-77.60%-87.19%-89.70%0.294.07100.00%-7,997.20%-7,828.56%
VYNE
VYNE THERAPEUTICS INC
$14.98M-71.90%-59.00%-95.60%-119.70%0.284.47100.00%-6,974.50%-6,973.88%
INMB
INMUNE BIO INC
$178.72M-119.40%-89.40%-136.56%700.80%0.272.64100.00%-81,592.00%-81,592.00%
ALGS
ALIGOS THERAPEUTICS INC
$47.15M-104.00%-51.00%-53.88%-160.90%0.297.56100.00%-1,628.70%-2,170.92%
AVXL
ANAVEX LIFE SCIENCES CORP
$685.54M-40.90%-36.40%-47.45%404.80%0.176.74N/AN/AN/A
IONS
IONIS PHARMACEUTICALS INC
$5.66B-92.10%-15.80%-14.55%-9.90%4.919.6698.50%-63.90%-51.99%
YMAB
Y-MABS THERAPEUTICS INC
$213.29M-30.60%-22.70%-32.92%-115.20%0.264.7781.80%-31.80%-34.78%
RLAY
RELAY THERAPEUTICS INC
$552.05M-44.20%-39.50%-43.73%-46.50%0.1119.96100.00%-4,341.50%-4,341.53%
HLVX
HILLEVAX INC
$92.76M-61.30%-49.00%-60.31%-85.30%0.1925.32N/AN/AN/A
BNTC
BENITEC BIOPHARMA INC
$421.89M-38.10%-35.50%-25.63%734.90%0.0814.80N/AN/AN/A
IFRX
INFLARX NV
$53.11M-64.00%-53.30%-63.13%-103.10%0.245.28-2,293.60%-34,466.40%-34,445.08%
MNPR
MONOPAR THERAPEUTICS
$204.98M-55.40%-51.50%-30.92%-301.30%0.0336.92N/AN/AN/A
ADCT
ADC THERAPEUTICS SA
$355.06MN/A-45.60%-46.44%-76.50%-2.144.4692.70%-197.60%-131.54%
CGEN
COMPUGEN LTD
$146.85M-24.50%-12.20%-10.16%-41.60%1.025.0970.20%-51.30%-34.78%
CLNN
CLENE INC
$36.83MN/A-93.40%-176.24%-113.50%-6.091.3678.90%-8,306.00%-7,326.57%
AXSM
AXSOME THERAPEUTICS INC
$5.13B-363.80%-48.90%-76.62%-153.90%10.222.0391.50%-64.40%-62.54%
FBIO
FORTRESS BIOTECH INC
$54.70M-241.60%-34.10%-25.89%-49.20%6.541.7267.40%-87.80%-46.78%
ASMB
ASSEMBLY BIOSCIENCES INC
$128.69M-131.80%-36.80%-75.57%-101.30%2.652.05N/AN/AN/A
CMMB
CHEMOMAB THERAPEUTICS LTD
$22.64M-106.70%-82.20%-126.75%-206.10%0.235.33N/AN/AN/A
JAZZ
JAZZ PHARMACEUTICALS PLC
$6.69B11.90%4.10%5.69%7.50%1.763.3888.80%11.90%14.44%
AVIR
ATEA PHARMACEUTICALS INC
$270.43M-31.30%-29.30%-33.14%-42.80%0.0719.94N/AN/AN/A
ABEO
ABEONA THERAPEUTICS INC
$315.13M-86.50%-38.20%-49.07%-40.40%1.404.90N/AN/AN/A
DAWN
DAY ONE BIOPHARMACEUTICALS INC
$676.09M-15.00%-13.00%-12.73%-25.20%0.1110.6295.00%-42.70%-38.25%
PHIO
PHIO PHARMACEUTICALS CORP
$10.89M-105.70%-89.20%-55.59%862.90%0.1010.58N/AN/AN/A
ZBIO
ZENAS BIOPHARMA INC
$432.15MN/AN/AN/AN/A0.176.47N/AN/AN/A
ABUS
ARBUTUS BIOPHARMA CORP
$676.09M-75.50%-55.80%-78.35%-92.50%0.486.01100.00%-1,195.90%-1,193.97%
IVVD
INVIVYD INC
$95.01M-165.20%-99.70%-263.57%2,600.20%0.921.5393.30%-389.00%-389.00%
BNTX
BIONTECH SE
$25.62B-4.00%-3.50%-3.71%-7.80%0.1210.1879.40%-27.90%-26.56%
NTHI
NEONC TECHNOLOGIES HOLDINGS INC
$106.74MN/AN/AN/AN/A-1.880.41N/AN/AN/A
NRSN
NEUROSENSE THERAPEUTICS LTD
$55.28MN/A-461.70%-395.28%388.00%0.772.21N/AN/AN/A
LQDA
LIQUIDIA CORP
$1.21B-170.30%-57.60%-67.82%-92.40%3.582.9358.10%-903.80%-800.35%
IBRX
IMMUNITYBIO INC
$2.71BN/A-109.40%-103.57%-24.00%-1.512.2299.80%-1,310.30%-844.37%
NRXP
NRX PHARMACEUTICALS INC
$59.47MN/A-460.00%95.82%166.60%-1.300.22N/AN/AN/A
IRD
OPUS GENETICS INC
$57.87M-270.30%-137.70%-245.11%911.10%4.781.98100.00%-429.40%-429.42%
ITRM
ITERUM THERAPEUTICS PLC
$39.64MN/A-83.80%-67.27%-138.40%-13.913.73N/AN/AN/A
SRPT
SAREPTA THERAPEUTICS INC
$3.56B-20.00%-6.90%-5.74%-4.30%2.034.0281.80%-11.10%-7.35%
ACTU
ACTUATE THERAPEUTICS INC
$169.71MN/A-339.70%541.38%279.10%-1.880.46N/AN/AN/A
NNNN
ANBIO BIOTECHNOLOGY
$1.23B14.80%13.70%13.80%44.90%0.1010.7171.90%29.00%28.99%
VERV
VERVE THERAPEUTICS INC
$549.12M-35.80%-27.60%-32.14%-33.90%0.309.84100.00%-303.60%-303.09%
LYEL
LYELL IMMUNOPHARMA INC
$143.83M-73.70%-61.00%-86.10%-75.40%0.287.49100.00%-576,762.10%-576,762.07%
IKT
INHIBIKASE THERAPEUTICS INC
$138.28M-79.00%-70.90%-42.63%-281.10%0.1011.01N/AN/AN/A
PROK
PROKIDNEY CORP
$245.29MN/A-15.00%-18.36%-22.70%-0.0410.96100.00%-22,362.10%-22,394.12%
ITOS
ITEOS THERAPEUTICS INC
$389.24M-21.40%-18.50%-18.98%-23.40%0.1714.13100.00%-373.70%-336.72%
LCTX
LINEAGE CELL THERAPEUTICS INC
$184.97M-22.20%-15.30%-16.43%5,088.20%0.433.8297.20%-169.60%-169.57%
COEP
COEPTIS THERAPEUTICS HOLDINGS INC
$29.38M-281.10%-111.20%-123.10%-229.30%0.930.8228.20%-15,698.00%-15,273.15%
TLSA
TIZIANA LIFE SCIENCES LTD
$172.77M-250.50%-101.10%-425.46%-666.20%1.871.02N/AN/AN/A
VNDA
VANDA PHARMACEUTICALS INC
$265.79M-8.30%-6.80%-10.53%-16.50%0.243.9394.30%-22.00%-27.63%
MREO
MEREO BIOPHARMA GROUP PLC
$438.84M-69.30%-57.30%-77.77%4,192.90%0.148.92N/AN/AN/A
ATYR
ATYR PHARMA INC
$462.82M-86.90%-64.80%-73.26%-74.00%0.307.80N/AN/AN/A
BDRX
BIODEXA PHARMACEUTICALS PLC
$0.00-88.10%-45.20%-59.66%3,668.10%0.781.75N/AN/AN/A
KLRS
KALARIS THERAPEUTICS INC
$49.37M-36.90%-32.60%-38.79%-570.40%0.6114.31N/AN/AN/A
ENSC
ENSYSCE BIOSCIENCES INC
$4.91M-176.20%-121.80%-237.48%-683.50%0.622.50N/AN/AN/A
ICU
SEASTAR MEDICAL HOLDING CORP
$12.47MN/A-313.30%-2,794.16%384.30%12.450.97100.00%-3,716.10%-3,688.55%
VRCA
VERRICA PHARMACEUTICALS INC
$57.62MN/A-145.60%-443.55%-170.80%-3.271.3471.60%-919.20%-789.72%
ARCT
ARCTURUS THERAPEUTICS HOLDINGS INC
$335.75M-27.40%-19.00%-29.66%-276.90%0.425.64100.00%-47.50%-58.30%
XNCR
XENCOR INC
$654.06M-31.90%-22.60%-20.82%-18.20%0.415.89100.00%-163.20%-133.60%
BBIO
BRIDGEBIO PHARMA INC
$7.55BN/A-82.00%-75.23%-26.00%-1.534.5795.40%-524.20%-430.76%
MDWD
MEDIWOUND LTD
$220.50M-74.10%-30.90%-43.05%-76.30%1.212.1514.40%-110.50%-105.70%
CVAC
CUREVAC NV
$1.25B29.60%24.40%30.83%84.20%0.157.6587.60%34.50%40.09%
CLSD
CLEARSIDE BIOMEDICAL INC
$62.17MN/A-114.20%-205.35%-53.50%-1.433.1972.30%-2,148.60%-2,098.74%
TRVI
TREVI THERAPEUTICS INC
$619.63M-58.40%-52.50%-47.31%-76.10%0.0815.38N/AN/AN/A
KURA
KURA ONCOLOGY INC
$557.54M-43.60%-29.10%-27.22%-36.40%1.048.07100.00%-267.50%-261.86%
EPIX
ESSA PHARMA INC
$74.13M-23.50%-22.90%-25.06%-96.80%0.0267.17N/AN/AN/A
SLN
SILENCE THERAPEUTICS PLC
$251.49M-2,380.90%-34.20%-41.31%-86.70%-0.648.8167.40%-256.30%-245.91%
CDTX
CIDARA THERAPEUTICS INC
$296.23M-132.70%-98.60%-128.03%831.10%0.353.87100.00%-60,589.70%-60,589.74%
PBM
PSYENCE BIOMEDICAL LTD
$2.23MN/A-583.50%465.76%5,423.00%-1.100.09N/AN/AN/A
RAPT
RAPT THERAPEUTICS INC
$137.58M-81.50%-70.20%-65.13%-157.70%0.0621.11N/AN/AN/A
ANAB
ANAPTYSBIO INC
$685.15M-282.50%-30.80%-37.19%-21.40%11.418.25100.00%-125.70%-125.66%
LXRX
LEXICON PHARMACEUTICALS INC
$243.69M-103.20%-55.00%-88.16%-60.30%1.422.2298.00%-568.00%-528.10%
CCCC
C4 THERAPEUTICS INC
$119.29M-45.90%-29.00%-37.01%-32.90%0.645.70100.00%-259.60%-259.27%
JBIO
JADE BIOSCIENCES INC
$5.60M-60.00%-54.30%-65.11%-103.60%0.0332.01N/AN/AN/A
BIVI
BIOVIE INC
$21.16M-102.80%-80.00%-82.42%1,054.90%0.139.32N/AN/AN/A
RNAC
CARTESIAN THERAPEUTICS INC
$270.44MN/A-10.30%-9.65%-20.90%-19.7812.34100.00%-124.40%-111.27%
ELAB
PMGC HOLDINGS INC
$2.86M-99.40%-75.60%-70.55%-1,676.80%0.098.9772.50%1,050.70%933.15%
VCEL
VERICEL CORP
$2.15B1.10%0.70%0.97%1.00%0.445.0172.50%1.20%1.57%
TNXP
TONIX PHARMACEUTICALS HOLDING CORP
$234.24M-121.00%-101.30%-73.00%-243.60%0.0712.3229.80%-1,313.90%-1,313.87%
INSM
INSMED INC
$17.98B-447.00%-52.70%-59.08%-45.80%17.185.8676.50%-265.90%-242.45%
ALZN
ALZAMEND NEURO INC
$2.38M-504.20%-149.10%-121.98%316.10%0.215.44N/AN/AN/A
SMMT
SUMMIT THERAPEUTICS INC
$14.69B-70.50%-57.90%-66.51%-84.70%0.1210.63N/AN/AN/A
RYTM
RHYTHM PHARMACEUTICALS INC
$4.00B-762.80%-45.70%-53.80%-81.10%11.803.3089.60%-127.10%-108.04%
TECX
TECTONIC THERAPEUTIC INC
$408.74M-30.90%-28.30%-19.44%1,185.10%0.0522.92N/AN/AN/A
LENZ
LENZ THERAPEUTICS INC
$816.24M-23.70%-22.60%-24.78%-29.70%0.0523.09N/AN/AN/A
HOTH
HOTH THERAPEUTICS INC
$17.17M-109.20%-100.20%-83.39%6,121.60%0.0715.08N/AN/AN/A
UPB
UPSTREAM BIO INC
$611.10MN/AN/AN/AN/A0.0247.43N/AN/AN/A
FATE
FATE THERAPEUTICS INC
$146.16M-51.50%-37.80%-47.47%-37.20%0.388.82100.00%-1,318.90%-1,318.93%
ANIX
ANIXA BIOSCIENCES INC
$107.59M-64.10%-60.40%-80.41%-72.00%0.138.89N/AN/AN/A
PTGX
PROTAGONIST THERAPEUTICS INC
$3.49B9.20%8.30%8.07%12.30%0.0817.26100.00%27.00%27.47%
GNLX
GENELUX CORP
$115.47M-93.00%-74.20%-94.30%-115.30%0.314.68N/AN/AN/A
MGNX
MACROGENICS INC
$95.90M-59.80%-23.50%-32.40%-79.80%1.843.2889.90%-36.20%-35.57%
ONCO
ONCONETIX INC
$2.47M-2,162.10%-136.60%-1,178.61%1,019.50%3.570.1747.40%-2,986.30%-2,899.46%
ALLR
ALLARITY THERAPEUTICS INC
$12.11M-151.70%-92.70%-124.13%364.90%0.592.66N/AN/AN/A
BTAI
BIOXCEL THERAPEUTICS INC
$9.45MN/A-83.80%-188.53%-28.10%-1.431.48-12.20%-2,163.20%-1,325.43%
OMER
OMEROS CORP
$199.21MN/A-51.80%-87.53%-20.40%-2.101.16N/AN/AN/A
NAMS
NEWAMSTERDAM PHARMA CO NV
$2.27B-32.60%-29.20%-24.10%1,904.80%0.0519.98100.00%-397.50%-397.45%
GOVX
GEOVAX LABS INC
$15.65M-512.00%-286.60%-309.93%2,565.60%0.373.62N/AN/AN/A
ORKA
ORUKA THERAPEUTICS INC
$470.25M-27.80%-25.60%-21.23%-52.50%0.0330.03N/AN/AN/A
HCWB
HCW BIOLOGICS INC
$7.84MN/A-90.10%2,785.82%-226.00%-4.070.07100.00%-7,160.80%-6,904.18%
NRIX
NURIX THERAPEUTICS INC
$909.49M-47.50%-36.10%-39.66%-50.10%0.286.26100.00%-369.40%-369.08%

Biotech Stocks FAQ

What are the best biotech stocks to buy right now in Jun 2025?

According to Zen Ratings, our proprietary rating system that evaluates 115 factors proven to drive growth in stocks and assigns each stock in our system an overall letter grade as well as 7 individual Component Grades for Value, Growth, Momentum, Sentiment, Safety, Financials, and proprietary AI algorithms, the 3 best biotechnology stocks to buy right now are:

1. Aurinia Pharmaceuticals (NASDAQ:AUPH)


Aurinia Pharmaceuticals (NASDAQ:AUPH) is the #1 top biotech stock out of 653 with a Zen Rating of A. Stocks with a rating of A have had an average return of +32.52% per year. Learn more.

The Component Grade breakdown for Aurinia Pharmaceuticals (NASDAQ:AUPH) is: Value: B, Growth: B, Momentum: C, Sentiment: A, Safety: C, Financials: A, and AI: C.

Aurinia Pharmaceuticals (NASDAQ:AUPH) has a Due Diligence Score of 62, which is 38 points higher than the biotech industry average of 24.

AUPH passed 20 out of 33 due diligence checks and has strong fundamentals. Aurinia Pharmaceuticals has seen its stock return 52.9% over the past year, overperforming other biotech stocks by 129 percentage points.

2. Exelixis (NASDAQ:EXEL)


Exelixis (NASDAQ:EXEL) is the #2 top biotech stock out of 653 with a Zen Rating of A. Stocks with a rating of A have had an average return of +32.52% per year. Learn more.

The Component Grade breakdown for Exelixis (NASDAQ:EXEL) is: Value: A, Growth: C, Momentum: C, Sentiment: A, Safety: C, Financials: A, and AI: C.

Exelixis (NASDAQ:EXEL) has a Due Diligence Score of 67, which is 43 points higher than the biotech industry average of 24.

EXEL passed 22 out of 33 due diligence checks and has strong fundamentals. Exelixis has seen its stock return 89.39% over the past year, overperforming other biotech stocks by 166 percentage points.

Exelixis has an average 1 year price target of $39.94, a downside of -3.97% from Exelixis's current stock price of $41.59.

Exelixis stock has a consensus Buy recommendation according to Wall Street analysts. Of the 16 analysts covering Exelixis, 31.25% have issued a Strong Buy rating, 18.75% have issued a Buy, 50% have issued a hold, while 0% have issued a Sell rating, and 0% have issued a Strong Sell.

3. Catalyst Pharmaceuticals (NASDAQ:CPRX)


Catalyst Pharmaceuticals (NASDAQ:CPRX) is the #3 top biotech stock out of 653 with a Zen Rating of A. Stocks with a rating of A have had an average return of +32.52% per year. Learn more.

The Component Grade breakdown for Catalyst Pharmaceuticals (NASDAQ:CPRX) is: Value: A, Growth: C, Momentum: C, Sentiment: A, Safety: D, Financials: A, and AI: C.

Catalyst Pharmaceuticals (NASDAQ:CPRX) has a Due Diligence Score of 73, which is 49 points higher than the biotech industry average of 24.

CPRX passed 24 out of 33 due diligence checks and has strong fundamentals. Catalyst Pharmaceuticals has seen its stock return 53.49% over the past year, overperforming other biotech stocks by 130 percentage points.

Catalyst Pharmaceuticals has an average 1 year price target of $32.50, an upside of 38.12% from Catalyst Pharmaceuticals's current stock price of $23.53.

Catalyst Pharmaceuticals stock has a consensus Strong Buy recommendation according to Wall Street analysts. Of the 4 analysts covering Catalyst Pharmaceuticals, 50% have issued a Strong Buy rating, 50% have issued a Buy, 0% have issued a hold, while 0% have issued a Sell rating, and 0% have issued a Strong Sell.

What are the biotech stocks with highest dividends?

Out of 5 biotech stocks that have issued dividends in the past year, the 3 biotech stocks with the highest dividend yields are:

1. Dominari Holdings (NASDAQ:DOMH)


Dominari Holdings (NASDAQ:DOMH) has an annual dividend yield of 6.58%, which is 5 percentage points higher than the biotech industry average of 1.63%.

Dominari Holdings's dividend payout ratio of -7.1% indicates that its high dividend yield might not be sustainable for the long-term.

2. Novo Nordisk (Ozempic) (NYSE:NVO)


Novo Nordisk (Ozempic) (NYSE:NVO) has an annual dividend yield of 2.02%, which is the same as the biotech industry average of 1.63%. Novo Nordisk (Ozempic)'s dividend payout is not stable, having dropped more than 10% ten times in the last 10 years. Novo Nordisk (Ozempic)'s dividend has shown consistent growth over the last 10 years.

Novo Nordisk (Ozempic)'s dividend payout ratio of 45.2% indicates that its dividend yield is sustainable for the long-term.

3. Royalty Pharma (NASDAQ:RPRX)


Royalty Pharma (NASDAQ:RPRX) has an annual dividend yield of 1.87%, which is the same as the biotech industry average of 1.63%. Royalty Pharma's dividend payout is stable, having never dropped by more than 10% in the last 10 years. Royalty Pharma's dividend has shown consistent growth over the last 10 years.

Royalty Pharma's dividend payout ratio of 34.4% indicates that its dividend yield is sustainable for the long-term.

Why are biotech stocks down?

Biotech stocks were down -1.4% in the last day, and down -1.07% over the last week. Biorestorative Therapies was the among the top losers in the biotechnology industry, dropping -16% yesterday.

BioRestorative Therapies shares are trading lower. The company announced the presentation of promising preliminary blinded data from the first 36 subjects in its ongoing Phase 2 clinical trial of BRTX-100.

What are the most undervalued biotech stocks?

Based on the Valuation rating, one of the 7 components of a stocks overall Zen Ratings grade, which evaluates factors including estimated earnings yield, earnings before interest and taxes/enterprise value, cash flow yield, free cash flow to price, and price-to-earnings growth (PEG ratio), the 3 most undervalued biotech stocks right now are:

1. Puma Biotechnology (NASDAQ:PBYI)


Puma Biotechnology (NASDAQ:PBYI) is the most undervalued biotech stock based on its Valuation Rating of A. Valuation is one of 7 Component Grades used to calculate the overall Zen Rating.

Puma Biotechnology has a valuation score of 43, which is 28 points higher than the biotech industry average of 15. It passed 3 out of 7 valuation due diligence checks.

Puma Biotechnology's stock has gained 0.9% in the past year. It has overperformed other stocks in the biotech industry by 77 percentage points.

2. Harmony Biosciences Holdings (NASDAQ:HRMY)


Harmony Biosciences Holdings (NASDAQ:HRMY) is the second most undervalued biotech stock based on its Valuation Rating of A. Valuation is one of 7 Component Grades used to calculate the overall Zen Rating.

Harmony Biosciences Holdings has a valuation score of 71, which is 56 points higher than the biotech industry average of 15. It passed 5 out of 7 valuation due diligence checks.

Harmony Biosciences Holdings's stock has gained 10.79% in the past year. It has overperformed other stocks in the biotech industry by 87 percentage points.

3. United Therapeutics (NASDAQ:UTHR)


United Therapeutics (NASDAQ:UTHR) is the third most undervalued biotech stock based on its Valuation Rating of A. Valuation is one of 7 Component Grades used to calculate the overall Zen Rating.

United Therapeutics has a valuation score of 43, which is 28 points higher than the biotech industry average of 15. It passed 3 out of 7 valuation due diligence checks.

United Therapeutics's stock has dropped -1.47% in the past year. It has overperformed other stocks in the biotech industry by 75 percentage points.

Are biotech stocks a good buy now?

53.31% of biotech stocks rated by analysts are a strong buy right now. On average, analysts expect biotech stocks to rise by 99.94% over the next year.

2.39% of biotech stocks have a Zen Rating of A (Strong Buy), 4.56% of biotech stocks are rated B (Buy), 35.57% are rated C (Hold), 36.66% are rated D (Sell), and 20.82% are rated F (Strong Sell).

What is the average p/e ratio of the biotechnology industry?

The average P/E ratio of the biotechnology industry is -108.97x.
WallStreetZen does not provide financial advice and does not issue recommendations or offers to buy stock or sell any security.

Information is provided 'as-is' and solely for informational purposes and is not advice. WallStreetZen does not bear any responsibility for any losses or damage that may occur as a result of reliance on this data.