| Name | Role | Date | Shares | Price | Value |
|---|---|---|---|---|---|
| Cynthia L. Feldmann | Director | 2026-03-05 | 3,098 | $152.32 | $471.89kBuy |
| Cynthia L. Feldmann | Director | 2026-03-05 | 3,098 | $237.21 | $734.88kSell |
| Julia Madsen | Sr. VP and GM Life Sciences | 2025-11-21 | 2,872 | $114.22 | $328.04kBuy |
| Julia Madsen | Sr. VP and GM Life Sciences | 2025-11-21 | 2,136 | $262.00 | $559.63kSell |
| Julia Madsen | Sr. VP and GM Life Sciences | 2025-11-21 | 2,136 | $147.05 | $314.10kBuy |
| Julia Madsen | Sr. VP and GM Life Sciences | 2025-11-21 | 2,872 | $262.00 | $752.46kSell |
| Renato Tamaro | V.P. Corporate Treasurer | 2025-11-18 | 3,536 | $182.22 | $644.33kBuy |
| Renato Tamaro | V.P. Corporate Treasurer | 2025-11-18 | 1,500 | $257.76 | $386.64kSell |
| Renato Tamaro | V.P. Corporate Treasurer | 2025-11-18 | 212 | $258.03 | $54.70kSell |
| Renato Tamaro | V.P. Corporate Treasurer | 2025-11-18 | 3,324 | $257.43 | $855.70kSell |
| Name | Hold | Shares | Value | Type |
|---|---|---|---|---|
| Vanguard Group Inc | 12.53% | 12,286,535 | $2.73B | Institution |
| Blackrock Inc | 9.22% | 9,041,433 | $2.01B | Institution |
| State Street Corp | 4.71% | 4,614,840 | $1.02B | Institution |
| Massachusetts Financial Services Co | 4.30% | 4,218,307 | $936.80M | Institution |
| Morgan Stanley | 3.92% | 3,839,818 | $852.75M | Institution |
| Geode Capital Management LLC | 2.57% | 2,523,620 | $560.45M | Institution |
| Orbis Allan Gray Ltd | 2.29% | 2,249,511 | $499.57M | Institution |
| Generation Investment Management LLP | 2.13% | 2,088,483 | $463.81M | Institution |
| Select Equity Group LP | 1.97% | 1,928,033 | $428.18M | Institution |
| Wellington Management Group LLP | 1.68% | 1,644,079 | $365.12M | Institution |