NASDAQ: SPRO
Spero Therapeutics Revenue

Spero Therapeutics revenue was $66.80M for the trailing 12 months ending Dec 31, 2025, with N/A growth year over year. Quarterly revenue for the quarter (Q4 2025) ending on Dec 31, 2025 was $41.3M, up 658.9% from last quarter. For the last reported fiscal year 2025 ending Dec 31, 2025, SPRO annual revenue was $66.8M, with 39.2% growth year-over-year.

SPRO past revenue growth

How has SPRO's revenue growth performed historically?

Company
39.24%
Industry
499.16%
Market
37.03%
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Revenue Growth vs Industry Performance
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Revenue Growth vs Market Performance
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Accelerating Revenue Growth Performance

SPRO revenue history

Current Revenue
$66.8M
Current Earnings
$8.6M
Current Profit Margin
12.8%

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SPRO Revenue History By Year

SPRO Yearly RevenueSPRO RevenueSPRO ChangeSPRO Revenue Growth
2025-12-31$66.80M$18.83M+39.24%
2024-12-31$47.98M-$55.80M-53.77%
2023-12-31$103.78M$50.27M+93.95%
2022-12-31$53.51M$35.25M+193.10%
2021-12-31$18.26M$8.93M+95.67%
2020-12-31$9.33M-$8.82M-48.59%
2019-12-31$18.15M$14.18M+357.56%
2018-12-31$3.97M$1.99M+100.40%
2017-12-31$1.98M$1.64M+490.75%
2016-12-31$335.00kN/AN/A
2015-12-31$0.00N/AN/A

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Spero Therapeutics Revenue FAQ

What was SPRO's revenue last quarter?

Spero Therapeutics (NASDAQ: SPRO) reported Q4 2025 revenue of $41.30 million up 174.51% year over year. In the same quarter last year, Spero Therapeutics's revenue was $15.04 million.

What was Spero Therapeutics's revenue in 2025?

Spero Therapeutics's annual revenue for the twelve months ending Dec 31, 2025 was $66.80 million, a 39.24% increase year over year.

How much does Spero Therapeutics make in a day?

Based on Spero Therapeutics annual revenue for the past five years, SPRO makes an average of $159,082.19 per day.

What was Spero Therapeutics's annual revenue growth in the past year?

As of Q2 2026, Spero Therapeutics's revenue has grown 39.24% year over year. This is 459.93 percentage points lower than the US Biotechnology industry revenue growth rate of 499.16%. Spero Therapeutics's revenue in the past year totaled $66.80 million.

How much does Spero Therapeutics make in a year?

Spero Therapeutics's revenue by year for the past five years is:
  • Spero Therapeutics's revenue for the twelve months ending Dec 31, 2025 was $66.80 million, a 39.24% increase year over year.
  • Spero Therapeutics's annual revenue for Dec 31, 2024 was $47.98 million, a 53.77% decrease from 2023.
  • Spero Therapeutics's annual revenue for 2023 was $103.78 million, a 93.95% increase from 2022.
  • Spero Therapeutics's annual revenue for 2022 was $53.51 million, a 193.1% increase from 2021.
  • Spero Therapeutics's annual revenue for 2021 was $18.26 million, a 95.67% increase from 2020.
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