| Name | Role | Date | Shares | Price | Value |
|---|---|---|---|---|---|
| Leslie V. Norwalk | Director | 2026-05-12 | 3,810 | $155.01 | $590.60kSell |
| Kyle Gano | Chief Executive Officer | 2026-02-13 | 1,210 | $124.12 | $150.19kSell |
| Kyle Gano | Chief Executive Officer | 2026-02-13 | 1,385 | $124.12 | $171.91kSell |
| Kyle Gano | Chief Executive Officer | 2026-02-13 | 5,378 | $124.12 | $667.52kSell |
| Kevin Charles Gorman | Director | 2026-02-13 | 2,901 | $124.12 | $360.07kSell |
| Kevin Charles Gorman | Director | 2026-02-13 | 3,024 | $124.12 | $375.34kSell |
| Jude Onyia | Chief Scientific Officer | 2026-02-13 | 1,466 | $124.12 | $181.96kSell |
| Jude Onyia | Chief Scientific Officer | 2026-02-13 | 1,452 | $124.12 | $180.22kSell |
| Jude Onyia | Chief Scientific Officer | 2026-02-13 | 10,755 | $124.12 | $1.33MSell |
| Matt Abernethy | Chief Financial Officer | 2026-02-13 | 5,378 | $124.12 | $667.52kSell |
| Name | Hold | Shares | Value | Type |
|---|---|---|---|---|
| Bvf Partners L P | 34.87% | 35,058,600 | $5.55B | Insider |
| Vanguard Portfolio Management LLC | 4.70% | 4,726,344 | $748.75M | Institution |
| Vanguard Capital Management LLC | 4.49% | 4,511,904 | $714.78M | Institution |
| Ubs Group Ag | 1.21% | 1,221,036 | $193.44M | Institution |
| Venrock Healthcare Capital Partners LP | 0.74% | 739,900 | $117.21M | Insider |
| Bryan E. Roberts | 0.74% | 739,900 | $117.21M | Insider |
| Anders D. Hove | 0.74% | 739,900 | $117.21M | Insider |
| Dimensional Fund Advisors LP | 0.71% | 711,762 | $112.76M | Institution |
| Bank Of New York Mellon Corp | 0.70% | 702,492 | $111.29M | Institution |
| Fiera Capital Corp | 0.65% | 651,255 | $103.17M | Institution |