| Name | Role | Date | Shares | Price | Value |
|---|---|---|---|---|---|
| Leslie V. Norwalk | Director | 2026-07-29 | 842 | $139.43 | $117.40kBuy |
| Leslie V. Norwalk | Director | 2026-07-28 | 1,250 | $182.01 | $227.51kSell |
| Ingrid Delaet | Chief Regulatory Officer | 2026-07-10 | 4,367 | $106.02 | $462.99kBuy |
| Ingrid Delaet | Chief Regulatory Officer | 2026-07-10 | 4,367 | $181.02 | $790.51kSell |
| Ingrid Delaet | Chief Regulatory Officer | 2026-07-09 | 8,433 | $178.72 | $1.51MSell |
| Darin Lippoldt | Chief Legal Officer | 2026-07-09 | 10,000 | $179.60 | $1.80MSell |
| Darin Lippoldt | Chief Legal Officer | 2026-07-09 | 10,000 | $81.49 | $814.90kBuy |
| Ingrid Delaet | Chief Regulatory Officer | 2026-07-09 | 8,433 | $103.52 | $872.98kBuy |
| Ingrid Delaet | Chief Regulatory Officer | 2026-07-08 | 2,737 | $178.54 | $488.67kSell |
| Ingrid Delaet | Chief Regulatory Officer | 2026-07-08 | 2,737 | $103.52 | $283.33kBuy |
| Name | Hold | Shares | Value | Type |
|---|---|---|---|---|
| Bvf Partners L P | 34.49% | 35,058,600 | $5.29B | Insider |
| Venrock Healthcare Capital Partners LP | 0.73% | 739,900 | $111.59M | Insider |
| Anders D. Hove | 0.73% | 739,900 | $111.59M | Insider |
| Bryan E. Roberts | 0.73% | 739,900 | $111.59M | Insider |
| Swedbank Ab | 0.64% | 651,082 | $98.20M | Institution |
| Kevin Charles Gorman | 0.50% | 511,293 | $77.11M | Insider |
| Gary A. Lyons | 0.50% | 505,714 | $76.27M | Insider |
| Paul W. Hawran | 0.35% | 360,144 | $54.32M | Insider |
| Wylie W. Vale | 0.23% | 231,372 | $34.90M | Insider |
| Assenagon Asset Management Sa | 0.22% | 222,606 | $33.57M | Institution |