| Name | Role | Date | Shares | Price | Value |
|---|---|---|---|---|---|
| Mark Brosius | SVP Chief Mfg and Supply Cha | 2025-12-15 | 464 | $548.49 | $254.50kSell |
| Mark Brosius | SVP Chief Mfg and Supply Cha | 2025-12-15 | 464 | $548.49 | $254.50kSell |
| Mark Brosius | SVP Chief Mfg and Supply Chain Officer | 2025-12-15 | 464 | $548.49 | $254.50kSell |
| Mark Brosius | SVP Chief Mfg and Supply Chain Officer | 2025-12-12 | 312 | $547.36 | $170.78kSell |
| Mark Brosius | SVP Chief Mfg and Supply Cha | 2025-12-12 | 4,500 | $547.36 | $2.46MSell |
| Mark Brosius | SVP Chief Mfg and Supply Cha | 2025-12-12 | 4,500 | $79.64 | $358.37kBuy |
| Mark Brosius | SVP Chief Mfg and Supply Cha | 2025-12-12 | 4,500 | $547.36 | $2.46MSell |
| Mark Brosius | SVP Chief Mfg and Supply Cha | 2025-12-12 | 4,500 | $79.64 | $358.37kBuy |
| Myriam Curet | EVP Chief Medical Officer | 2025-12-10 | 104 | $229.39 | $23.86kBuy |
| Myriam Curet | EVP Chief Medical Officer | 2025-12-10 | 104 | $559.90 | $58.23kSell |
| Name | Hold | Shares | Value | Type |
|---|---|---|---|---|
| Vanguard Group Inc | 9.48% | 33,599,661 | $19.33B | Institution |
| Blackrock Inc | 8.90% | 31,543,936 | $18.15B | Institution |
| State Street Corp | 4.38% | 15,539,327 | $8.94B | Institution |
| Price T Rowe Associates Inc | 3.62% | 12,818,790 | $7.38B | Institution |
| Geode Capital Management LLC | 2.33% | 8,273,676 | $4.76B | Institution |
| Capital World Investors | 2.18% | 7,728,492 | $4.45B | Institution |
| Morgan Stanley | 1.78% | 6,302,369 | $3.63B | Institution |
| Fmr LLC | 1.41% | 4,999,960 | $2.88B | Institution |
| Bank Of New York Mellon Corp | 1.16% | 4,123,290 | $2.37B | Institution |
| Alliancebernstein LP | 1.14% | 4,042,414 | $2.33B | Institution |