| Name | Role | Date | Shares | Price | Value |
|---|---|---|---|---|---|
| John A. Fallon | Director | 2025-11-12 | 19,853 | $9.33 | $185.23kBuy |
| John A. Fallon | Director | 2025-11-12 | 15,000 | $16.49 | $247.35kBuy |
| Vikram Karnani | President and CEO | 2025-11-12 | 8,983 | $47.35 | $425.35kSell |
| John A. Fallon | Director | 2025-11-12 | 34,853 | $47.21 | $1.65MSell |
| Colleen Tupper | EVP Chief Financial Officer | 2025-11-06 | 4,858 | $41.28 | $200.52kSell |
| Colleen Tupper | EVP Chief Financial Officer | 2025-11-06 | 25,142 | $40.38 | $1.02MSell |
| Thomas B. Smith | EVP and Chief Medical Officer | 2025-08-29 | 17,478 | $38.42 | $671.57kSell |
| Scott Dreyer | EVP Chief Commercial Officer | 2025-08-18 | 16,389 | $38.21 | $626.17kSell |
| Scott Dreyer | EVP Chief Commercial Officer | 2025-08-18 | 16,389 | $21.34 | $349.74kBuy |
| Gino Santini | Director | 2025-08-15 | 15,000 | $13.45 | $201.75kBuy |
| Name | Hold | Shares | Value | Type |
|---|---|---|---|---|
| David Hirsch | 20.37% | 6,438,798 | $308.48M | Insider |
| Rubric Capital Management LP | 19.90% | 6,290,486 | $301.38M | Insider |
| Longitude Capital Partners LLC | 17.85% | 5,643,684 | $270.39M | Insider |
| Blackrock Inc | 16.38% | 5,178,044 | $248.08M | Institution |
| Skyline Venture Partners V LP | 16.13% | 5,099,832 | $244.33M | Insider |
| Rubric Capital Management LP | 8.94% | 2,826,498 | $135.42M | Institution |
| Eventide Asset Management LLC | 7.56% | 2,390,912 | $114.55M | Institution |
| Vanguard Group Inc | 7.04% | 2,226,378 | $106.67M | Institution |
| Yasunori Kaneko | 6.80% | 2,150,186 | $103.02M | Insider |
| Frazier Healthcare VI LP | 5.97% | 1,887,332 | $90.42M | Insider |