| Name | Role | Date | Shares | Price | Value |
|---|---|---|---|---|---|
| David Dieter | EVP General Counsel | 2026-03-18 | 13,976 | $34.92 | $488.10kSell |
| David Dieter | EVP General Counsel | 2026-03-17 | 8,840 | $35.72 | $315.76kSell |
| David Dieter | EVP General Counsel | 2026-03-09 | 6,224 | $36.65 | $228.11kSell |
| Scott Dreyer | EVP Chief Commercial Officer | 2026-03-03 | 3,559 | $40.99 | $145.88kSell |
| Scott Dreyer | EVP Chief Commercial Officer | 2026-03-03 | 46,417 | $40.36 | $1.87MSell |
| Vikram Karnani | President and CEO | 2026-02-10 | 11,296 | $46.75 | $528.09kSell |
| Thomas B. Smith | EVP and Chief Medical Officer | 2026-02-10 | 5,897 | $46.75 | $275.68kSell |
| David Dieter | EVP General Counsel | 2026-02-10 | 2,781 | $46.75 | $130.01kSell |
| Colleen Tupper | EVP Chief Financial Officer | 2026-02-10 | 26,679 | $46.75 | $1.25MSell |
| Colleen Tupper | EVP Chief Financial Officer | 2026-02-10 | 11,861 | $46.75 | $554.50kSell |
| Name | Hold | Shares | Value | Type |
|---|---|---|---|---|
| David Hirsch | 20.28% | 6,438,798 | $222.65M | Insider |
| Rubric Capital Management LP | 19.81% | 6,290,486 | $217.53M | Insider |
| Longitude Capital Partners LLC | 17.77% | 5,643,684 | $195.16M | Insider |
| Skyline Venture Partners V LP | 16.06% | 5,099,832 | $176.35M | Insider |
| Blackrock Inc | 16.06% | 5,099,702 | $176.35M | Institution |
| Vanguard Group Inc | 7.11% | 2,256,254 | $78.02M | Institution |
| Yasunori Kaneko | 6.77% | 2,150,186 | $74.35M | Insider |
| Patrick J. Heron | 5.94% | 1,887,332 | $65.26M | Insider |
| Frazier Healthcare VI LP | 5.94% | 1,887,332 | $65.26M | Insider |
| Eventide Asset Management LLC | 5.91% | 1,876,239 | $64.88M | Institution |