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Best Biotech Stocks to Buy Now (2025)

Top biotech stocks in 2025 ranked by overall Zen Rating. "A" Rated stocks have returned an average of +32.52% per year, and are the best biotech stocks to buy now. Learn More.

According to Zen Ratings, our proprietary rating system that evaluates 115 factors proven to drive growth in stocks and assigns each stock in our system an overall letter grade as well as 7 individual Component Grades for Value, Growth, Momentum, Sentiment, Safety, Financials, and proprietary AI algorithms, the 3 best biotechnology stocks to buy right now are:

Mimedx Group (NASDAQ:MDXG) is the #1 top biotech stock out of 624 with a Zen Rating of A. Stocks with a rating of A have had an average return of +32.52% per year. Learn more.

The Component Grade breakdown for Mimedx Group (NASDAQ:MDXG) is: Value: B, Growth: B, Momentum: C, Sentiment: A, Safety: C, Financials: A, and AI: C.

Mimedx Group (NASDAQ:MDXG) has a Due Diligence Score of 48, which is 25 points higher than the biotech industry average of 23.

MDXG passed 15 out of 33 due diligence checks and has strong fundamentals. Mimedx Group has seen its stock return 5.47% over the past year, overperforming other biotech stocks by 65 percentage points.

Mimedx Group has an average 1 year price target of $12.00, an upside of 59.57% from Mimedx Group's current stock price of $7.52.

Mimedx Group stock has a consensus Strong Buy recommendation according to Wall Street analysts. Of the 1 analyst covering Mimedx Group, 100% have issued a Strong Buy rating, 0% have issued a Buy, 0% have issued a hold, while 0% have issued a Sell rating, and 0% have issued a Strong Sell.

Incyte (NASDAQ:INCY) is the #2 top biotech stock out of 624 with a Zen Rating of A. Stocks with a rating of A have had an average return of +32.52% per year. Learn more.

The Component Grade breakdown for Incyte (NASDAQ:INCY) is: Value: A, Growth: B, Momentum: C, Sentiment: B, Safety: C, Financials: B, and AI: B.

Incyte (NASDAQ:INCY) has a Due Diligence Score of 60, which is 37 points higher than the biotech industry average of 23.

INCY passed 19 out of 33 due diligence checks and has strong fundamentals. Incyte has seen its stock return 34.09% over the past year, overperforming other biotech stocks by 93 percentage points.

Incyte has an average 1 year price target of $91.54, a downside of -9.88% from Incyte's current stock price of $101.57.

Incyte stock has a consensus Buy recommendation according to Wall Street analysts. Of the 13 analysts covering Incyte, 53.85% have issued a Strong Buy rating, 0% have issued a Buy, 38.46% have issued a hold, while 7.69% have issued a Sell rating, and 0% have issued a Strong Sell.

Biocryst Pharmaceuticals (NASDAQ:BCRX) is the #3 top biotech stock out of 624 with a Zen Rating of A. Stocks with a rating of A have had an average return of +32.52% per year. Learn more.

The Component Grade breakdown for Biocryst Pharmaceuticals (NASDAQ:BCRX) is: Value: B, Growth: A, Momentum: D, Sentiment: A, Safety: C, Financials: B, and AI: C.

Biocryst Pharmaceuticals (NASDAQ:BCRX) has a Due Diligence Score of 15, which is -8 points lower than the biotech industry average of 23. Although this number is below the industry average, our proven quant model rates BCRX as a "A".

BCRX passed 5 out of 33 due diligence checks and has weak fundamentals. Biocryst Pharmaceuticals has seen its stock lose -6.67% over the past year, overperforming other biotech stocks by 53 percentage points.

Biocryst Pharmaceuticals has an average 1 year price target of $20.30, an upside of 195.92% from Biocryst Pharmaceuticals's current stock price of $6.86.

Biocryst Pharmaceuticals stock has a consensus Strong Buy recommendation according to Wall Street analysts. Of the 10 analysts covering Biocryst Pharmaceuticals, 40% have issued a Strong Buy rating, 50% have issued a Buy, 10% have issued a hold, while 0% have issued a Sell rating, and 0% have issued a Strong Sell.

Out of 4 biotech stocks that have issued dividends in the past year, the 3 biotech stocks with the highest dividend yields are:

Dominari Holdings (NASDAQ:DOMH) has an annual dividend yield of 11.09%, which is 8 percentage points higher than the biotech industry average of 2.77%.

Dominari Holdings's dividend payout ratio of -13.4% indicates that its high dividend yield might not be sustainable for the long-term.

Royalty Pharma (NASDAQ:RPRX) has an annual dividend yield of 2.33%, which is the same as the biotech industry average of 2.77%. Royalty Pharma's dividend payout is stable, having never dropped by more than 10% in the last 10 years. Royalty Pharma's dividend has shown consistent growth over the last 10 years.

Royalty Pharma's dividend payout ratio of 37.2% indicates that its dividend yield is sustainable for the long-term.

Bio Techne (NASDAQ:TECH) has an annual dividend yield of 0.52%, which is -2 percentage points lower than the biotech industry average of 2.77%. Bio Techne's dividend payout is not stable, having dropped more than 10% one times in the last 10 years. Bio Techne's dividend has not shown consistent growth over the last 10 years.

Bio Techne's dividend payout ratio of 68.1% indicates that its dividend yield is sustainable for the long-term.

Biotech stocks were down -2.06% in the last day, and down -1.34% over the last week. Uniqure Nv was the among the top losers in the biotechnology industry, dropping -49.34% yesterday.

uniQure shares are trading lower after the company announced that it believes that the FDA currently no longer agrees that data from the Phase I/II studies of AMT-130 in comparison to an external control may be adequate to provide the primary evidence in support of a BLA submission.

Based on the Valuation rating, one of the 7 components of a stocks overall Zen Ratings grade, which evaluates factors including estimated earnings yield, earnings before interest and taxes/enterprise value, cash flow yield, free cash flow to price, and price-to-earnings growth (PEG ratio), the 3 most undervalued biotech stocks right now are:

Harmony Biosciences Holdings (NASDAQ:HRMY) is the most undervalued biotech stock based on its Valuation Rating of A. Valuation is one of 7 Component Grades used to calculate the overall Zen Rating.

Harmony Biosciences Holdings has a valuation score of 71, which is 57 points higher than the biotech industry average of 14. It passed 5 out of 7 valuation due diligence checks.

Harmony Biosciences Holdings's stock has dropped -11.26% in the past year. It has overperformed other stocks in the biotech industry by 48 percentage points.

Puma Biotechnology (NASDAQ:PBYI) is the second most undervalued biotech stock based on its Valuation Rating of A. Valuation is one of 7 Component Grades used to calculate the overall Zen Rating.

Puma Biotechnology has a valuation score of 43, which is 29 points higher than the biotech industry average of 14. It passed 3 out of 7 valuation due diligence checks.

Puma Biotechnology's stock has gained 70.85% in the past year. It has overperformed other stocks in the biotech industry by 130 percentage points.

Rigel Pharmaceuticals (NASDAQ:RIGL) is the third most undervalued biotech stock based on its Valuation Rating of A. Valuation is one of 7 Component Grades used to calculate the overall Zen Rating.

Rigel Pharmaceuticals has a valuation score of 29, which is 15 points higher than the biotech industry average of 14. It passed 2 out of 7 valuation due diligence checks.

Rigel Pharmaceuticals's stock has gained 117.84% in the past year. It has overperformed other stocks in the biotech industry by 177 percentage points.

59.2% of biotech stocks rated by analysts are a strong buy right now. On average, analysts expect biotech stocks to rise by 63.01% over the next year.

3.08% of biotech stocks have a Zen Rating of A (Strong Buy), 5.13% of biotech stocks are rated B (Buy), 43.74% are rated C (Hold), 33.26% are rated D (Sell), and 14.78% are rated F (Strong Sell).